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Možnosti fyzioterapie u pacientů s instabilitou ramenního kloubu
BOČKOVÁ, Markéta
This bachelor thesis deals with the problem of instability of the shoulder joint and the possibilities of its physiotherapy. The thesis is divided into a theoretical and a practical part. The first aim of the thesis is to present the possibilities of physiotherapy for patients with instability of the shoulder joint. The second aim is to present therapeutic procedures for specific patients with shoulder joint instability using case studies. The theoretical part of the thesis describes the anatomy and kinesiology of the brachial plexus, followed by the characteristics and classification of instabilities. The theory is complemented by clinical examinations of the shoulder joint. The practical part of the study is a qualitative research, which is described in the form of case studies. At the beginning of the thesis I focus on the possibilities of physiotherapy of the given problem. Therapies that were used aimed at stabilization of the shoulder joint and strengthening of the brachial plexus muscles. The research consists of three probands, women aged 20-40 years with chronic pain in the shoulder joint area with concomitant instability due to degenerative changes. An initial kinesiological analysis was performed, based on which a short-term and long-term rehabilitation plan was drawn up and therapy was prescribed. A gradual increase in range of motion with concomitant increase in muscle strength was observed in all probands during therapy. In two of the three patients, pain in the shoulder joint area was also relieved. The results of the case studies were summarized in the conclusion of the bachelor thesis. The thesis can serve physiotherapists in practice as inspiration for therapeutic procedures.
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Furniture
Bocková, Markéta ; Mitura, Vojtěch (referee) ; Tobola, Ondřej (advisor)
Furniture design in the form of a modular shelf system designed to store and display alcohol bottles. The aim of the work is a combination of traditional liquer cabinet and sector display units.
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Study of biomolecular interactions by the method of surface plasmon resonance
Bocková, Markéta ; Homola, Jiří (advisor)
Title: Study of biomolecular interactions by the method of surface plasmon resonance Author: Markéta Bocková Department: Department of Biochemistry, Faculty of Science Supervisor: Prof. Jiří Homola, Ph.D., DSc., Institute of Photonics and Electronics of the Czech Academy of Sciences Abstract: In this diploma work, a surface plasmon resonance (SPR) biosensor technology was exploited to study two different classes of molecular interactions: hybridization of partially complementary oligonucleotides (ONs) and interactions between enzymes and peptides involved in pathogenesis of Alzheimer disease (AD). In particular, the study of interactions between ONs was focused on determining kinetic parameters of the hybridization proces. It was found that the association equilibrium constant decreases with the increasing surface probe density. An SPR biosensor-based method for rapid and sensitive detection of the 17-HSD10 enzyme and its complex with amyloid β (Aβ) peptides was designed and developed. It was demonstrated that the developed method is capable of detecting 17β-HSD10/Aβs complex in real cerebrospinal fluid (CSF) samples and that CSF samples from AD patients exhibited elavated levels of 17β- HSD10/Aβs complex compared to the control groups. The research reported in this thesis resulted in two publications in...
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Multifunctional biomolecular assemblies for parallelized analysis of biomolecular interactions
Bocková, Markéta ; Homola, Jiří (advisor) ; Brynda, Eduard (referee) ; Procházka, Marek (referee)
Title: Multifunctional biomolecular assemblies for parallelized analysis of biomolecular interactions Author: Markéta Bocková Department / Institute: Institute of Physics, Charles University Supervisor of the doctoral thesis: Prof. Jiří Homola, Ph.D., DSc., Institute of Photonics and Electronics, The Czech Academy of Sciences Abstract: Surface plasmon resonance (SPR) biosensors represent the most advanced optical method for the direct, real-time monitoring of biomolecular interactions without the need for labelling. This doctoral thesis aims to advance the SPR biosensor method and to expand its utility in the investigation of biomolecular interactions. This encompasses activities on two major fronts of SPR biosensor research - immobilization methods and biosensing methodologies. Methods for the immobilization of biomolecules were researched with the aim of enabling the immobilization of a broad range of biomolecules on the SPR biosensor surface in a spatially controlled manner. The development of novel biosensing methodologies was pursued in order to address the current limitations of SPR biosensors associated with non-specific adsorption and limited analyte transport, and thus to improve the accuracy and robustness of SPR biosensor measurements. Finally, advances in the development of immobilization...
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Furniture
Bocková, Markéta ; Mitura, Vojtěch (referee) ; Tobola, Ondřej (advisor)
Furniture design in the form of a modular shelf system designed to store and display alcohol bottles. The aim of the work is a combination of traditional liquer cabinet and sector display units.
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Study of biomolecular interactions by the method of surface plasmon resonance
Bocková, Markéta ; Homola, Jiří (advisor)
Title: Study of biomolecular interactions by the method of surface plasmon resonance Author: Markéta Bocková Department: Department of Biochemistry, Faculty of Science Supervisor: Prof. Jiří Homola, Ph.D., DSc., Institute of Photonics and Electronics of the Czech Academy of Sciences Abstract: In this diploma work, a surface plasmon resonance (SPR) biosensor technology was exploited to study two different classes of molecular interactions: hybridization of partially complementary oligonucleotides (ONs) and interactions between enzymes and peptides involved in pathogenesis of Alzheimer disease (AD). In particular, the study of interactions between ONs was focused on determining kinetic parameters of the hybridization proces. It was found that the association equilibrium constant decreases with the increasing surface probe density. An SPR biosensor-based method for rapid and sensitive detection of the 17-HSD10 enzyme and its complex with amyloid β (Aβ) peptides was designed and developed. It was demonstrated that the developed method is capable of detecting 17β-HSD10/Aβs complex in real cerebrospinal fluid (CSF) samples and that CSF samples from AD patients exhibited elavated levels of 17β- HSD10/Aβs complex compared to the control groups. The research reported in this thesis resulted in two publications in...
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