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Using Heck reaction for aromatic ring formation in the synthesis of polycyclic compounds
Bažíková, Ema ; Matoušová, Eliška (advisor) ; Míšek, Jiří (referee)
This bachelor's thesis focuses on the synthesis of a polycarbocyclic compound with naphthalene core and the following oxidation to the corresponding ortho-naphthoquinone. The naphthalene and naphthoquinone skeleton can be found in many natural products with interesting biological properties. This thesis extends the scope of a method developed by our group for the synthesis of naturally occurring ortho-naphthoquinones. The key step of the synthesis was to form an aromatic ring using the Heck reaction. Keywords: synthesis, polycyclic compounds, naphthalenes, catalysis, Heck reaction

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1 Baziková, Eliška
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