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National Repository of Grey Literature

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Analýza vybraných genových polymorfismů a její význam pro individualizovanou farmakoterapii ŘEŽÁBKOVÁ, Kristina This thesis deals with the metabolism of xenobiotics and the fact that it may be influenced by genetic polymorphisms in pharmacogens. In the experimental part, samples of volunteers and patients were tested by several methods of molecular biology detecting these polymorphisms and the results were interpreted and compared on the basis of available studies. Furthermore, the work highlights methods that would lead to successful individualized pharmacotherapy in similar clinical trials. Detailed record

Ateroskleróza a genetický vliv polymorfismu v genu MTHFR ŘEŽÁBKOVÁ, Kristina The aim of this work is to summarize the risk factors of atherosclerosis, and mostly highlight possible connection and impact of polymorphisms in the gene of methylentetrahydrofolate reductase (MTHFR). Further aim was to describe newly discovered polymorphisms that are often underestimated in present clinical examination Detailed record

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1	Řežábková, Kateřina

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