Original title:
Analýza vybraných genových polymorfismů a její význam pro individualizovanou farmakoterapii
Authors:
ŘEŽÁBKOVÁ, Kristina Document type: Master’s theses
Year:
2020
Language:
cze Abstract:
This thesis deals with the metabolism of xenobiotics and the fact that it may be influenced by genetic polymorphisms in pharmacogens. In the experimental part, samples of volunteers and patients were tested by several methods of molecular biology detecting these polymorphisms and the results were interpreted and compared on the basis of available studies. Furthermore, the work highlights methods that would lead to successful individualized pharmacotherapy in similar clinical trials.
Keywords:
drug metabolism; pharmacogenetics; pharmacogenomics; pharmacology; farmakogenetika; farmakogenomika; farmakologie; metabolismus léčiv Citation: ŘEŽÁBKOVÁ, Kristina. Analýza vybraných genových polymorfismů a její význam pro individualizovanou farmakoterapii. České Budějovice, 2020. diplomová práce (Mgr.). JIHOČESKÁ UNIVERZITA V ČESKÝCH BUDĚJOVICÍCH. Přírodovědecká fakulta
Institution: University of South Bohemia in České Budějovice
(web)
Document availability information: Fulltext is available in the Digital Repository of University of South Bohemia. Original record: http://www.jcu.cz/vskp/55915