National Repository of Grey Literature 24 records found  beginprevious15 - 24  jump to record: Search took 0.01 seconds. 
Design a syntéza 5,6-disubstituovaných uracilových derivátů jako účinných inhibitorů thymidinfosforylasy
Nencka, Radim ; Votruba, Ivan ; Hřebabecký, Hubert ; Tloušťová, Eva ; Horská, Květoslava ; Masojídková, Milena ; Holý, Antonín
We report on a series of novel 5,6-disubstituted uracils with significant inhibitory activity against human and Escherichia coli thymidine phosphorylases.
N6-methyl-AMP-hydrolasa aktivuje N6-substituované purinové ANPs
Schinkmanová, Markéta ; Votruba, Ivan ; Holý, Antonín
Identification and characterization of a new enzyme, N6-methyl-AMP aminohydrolase, that is responsible for the conversion of N6-cyclopropyl-PMEDAP to biologically active PMEG.
Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds
Otmar, Miroslav ; Masojídková, Milena ; Votruba, Ivan ; Holý, Antonín
2,6-Diamino-9-benzyl-9-deazapurine and 9-benzyl-2,6-bis(benzylamino)-9-deazapurine were synthesized by reductive cyclization of the corresponding 6-cyanomethyl-5-nitropyrimidines. Both compounds exhibit cytostatic activity in human T-lymphoblastoid CCRF-CEM cells.

National Repository of Grey Literature : 24 records found   beginprevious15 - 24  jump to record:
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