|
|
The role of laypersons in the ethics committee for assessment of clinical research in the Czech Republic
Kašková, Petra ; Doskočil, Ondřej (advisor) ; Šimek, Jiří (referee)
The clinical research is an indispensable part of the progress in medicine, therapy, but also in diagnosis. It is really necessary to realize the complexity of the ethical issues to explore the unknown on a human body. When ethically considerating it is necessary to come from the respect and protection of the dignity and human rights who take part in the clinical trials and these interests should always prioritize over the scientific and social interests. A crucial role in the clinical research regulation has the ethics committee. Members of the ethics committees shall have some professional behaviour, some experience and moral credit to be able to review clinical trials. Just members of the ethics committes can answer the queries regarding the mission and the purpose of the ethics committees work at all. Ethics committees have different representation in different countries. Ethics committees in the Czech Republic are composed of the experts - doctors and the laypersons, so lay people representing especially patients. In the theoretical section we present the history of the clinical research and impact of the research ethics committee. We present informed consent as a key document for patients entering the clinical trials. We also describe the activities and legislation of the ethics committee and...
|
|
|
Patients'Recruitment Issues in Clinical Trials
Hrubá, Dagmar ; Doskočil, Ondřej (advisor) ; Štegmannová, Ingrid (referee)
This thesis examines patient recruitment in clinical trials. It is a current and pressing issue, which is not sufficiently embedded in the thinking of doctors and patients, their patterns of communication, and more broadly in the traditional doctor-patient relationship, which continues to be burdened by post-socialist paternalism. The formal framework and ethics have been developed relatively recently, and their application causes confusion to all participants regarding how to proceed in specific situations. In addition, the choice of topic, and especially the form of dealing with the topic, was motivated by the relative lack of academic resources and publications in the field. The theoretical section of the thesis defines clinical research and its phases, and introduces basic terminology and documents closely linked to clinical research. In addition, it focuses on research ethics, thoroughly examining the issue of informed consent - a fundamental document necessary for recruiting a patient in a clinical trial. Finally, one chapter of the thesis focuses on the issue of medical literacy, the level of which is integral to the participants' understanding of the importance of clinical research, and directly affects participants' decision-making. The empirical section is divided into two parts. The...
|
|
|
Beginnings of Theology and Theological Anthropology in the Works of Caecilius Firmianus Lactantius
DOSKOČIL, Ondřej
The dissertation aims to highlight Lactantius´s position among other authors of Christian antiquity and tries to analyze and assess Lactantius´s views pertaining to selected theological topics. First two chapters summarize available findings on Lactantius´s life and integrate his work into the context of early Christian literature. The following part of the dissertation discusses Lactantius´s apologetic method as well as his ideological points of departure and pays attention to his relation toward ancient culture. The focal point of the dissertation lies in the assessment of Lactantius´s views of selected theological issues, such as the teaching about a sole God, teaching about creation, Christology, soteriology, ecclesiology, eschatology, and anthropology. The dissertation espacially looks into overlapping of ancient and Christian world of ideas as they are mirrored in Lactantius´s theological considerations.
|
guest ::
RSS feed.