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Analysis of antibiotic administration in open appendectomies in pediatric patients.
Šugrová, Kristína ; Rejmanová, Anna (advisor) ; Šorf, Aleš (referee)
Analysis of antibiotic administration in open appendectomies in pediatric patients Author: Kristína Šugrová Tutor: PharmDr. Anna Rejmanová, Ph.D. Consultant: PharmDr. Petra Rozsívalová Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Appendicitis represents the most frequent indication to a surgical abdominal intervention in population of paediatric patients. In case of complications, such as abscess, periappendicular infiltrate or perforation with peritonitis, it can even lead to a life- threatening condition. The aim of this study was to analyse antibiotic prophylaxis (AP) in paediatric patients undergoing open appendectomy, as well as antibiotic treatment of complicated appendicitis. Another aim was to compare the administration of antibiotics (ATB) before and after the implementation of recommended hospital procedures (RHP). Subsequently, to monitor the incidence of complications and length of hospital stay and their association with ATB administration and other risk factors. Methods: An unicentric retrospective study was carried out. Patients aged ≤ 18 years who underwent an open appendectomy at the Department of Paediatric Surgery and Traumatology at the University Hospital in Hradec Králové between years 2014 and...
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