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Natural and experimental definitive hosts of Fascioloides magna and Fasciola hepatica.
Melounová, Klára ; Kašný, Martin (advisor) ; Novobilský, Adam (referee)
Fascioloides magna (giant liver fluke) and Fasciola hepatica (liver fluke) are veterinary and medically important endoparasites belonging to the class Trematoda, subclass Digenea. They are the causative agents of the diseases fascioloidosis (F. magna) and fascioliasis (F. hepatica). They can infect a wide range of definitive hosts to which they cause serious health problems often leading to death. The typical final hosts of F. magna are primarily members of free living cervids, but this fluke can also occasionally occurs in domestic bovids. In contrast to this, F. hepatica is mostly parasite of domestic animals and rarely of cervids. The typical localization of both trematodes inside the definitive host is primarily the liver tissue - F. magna liver pseudocyst and F. hepatica bile ducts. In the liver tissue both flukes cause significant damage. Each species of host developed specific defense system to the invasion, some of them are quite resistant to the infection, some of them susceptive. Key words: Fluke, Fascioloides magna, Fasciola hepatica, definitive hosts, experimental hosts, pathogenicity, interaction.
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