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Voltammetric Behavior of Folates and Related Substances Using Silver Solid Amalgam Electrode
Bandžuchová, L. ; Šelešovská, R. ; Navrátil, Tomáš ; Chýlková, J.
The possibility of application of silver solid amalgam electrode in voltammetric analysis of compounds with folate structure (folic acid, methotrexate, leucovorin) and substances, which play an important role in its metabolism (riboflavin, hydroxocobalamin) has been investigated. Cyclic voltammetry, DC voltammetry and Elimination voltammetry with linear scan has been used for study of voltammetric behavior of mentioned substances and for elucidation of electrochemical reactions. Differential pulse voltammetry has been applied for development of sensitive methods of determination for investigated electroactive compounds. The proposed methods were successfully applied for real samples analysis. Obtained results have been compared with those achieved using HMDE.

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