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National Repository of Grey Literature

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Enhancing Reliability and Benchmarking Performance of Agar Plate Handling Algorithms for Laboratory Automation Robots Kalivodová, Tereza ; Nohel, Michal (referee) ; Mézl, Martin (advisor) Tato bakalářská práce zkoumá problematiku vzorkové přípravy v oblasti mikrobiologie a lékařské diagnostiky s důrazem na automatizovaný robotický systém MBT Pathfinder, vyvinutý firmou \bruker. S využitím digitálních obrazových technik a konvolučních neuronových sítí se práce zaměřuje na zdokonalení algoritmu pro identifikaci pozice mikrobiálních kolonií v systému MBT Pathfinder. Praktická část práce prezentuje inovativní přístupy k optimalizaci kritických kroků vzorkové přípravy s cílem eliminovat chyby a zvýšit efektivitu procesu. Výsledky této práce mohou posílit spolehlivost mikrobiologických analýz v oblasti lékařské diagnostiky a mikrobiologického výzkumu. Detailed record

Image-Based Clustering of Microbial Colonies Láncoš, Jan ; Kišš, Martin (referee) ; Beneš, Karel (advisor) Laboratorní analýza mikrobiálních kolonií pěstovaných na Petriho miskách je v současné době předmětem intenzivního výzkumu ve snaze o dosažení totální laboratorní automatizace. Jádro tohoto problému spočívá v přesné lokalizaci kolonií při obrazové analýze. Současná řešení nejčastěji využívají strojové učení, které je však obecně závislé na kvalitních datech, kterých je v tomto odvětví k dispozici jen velmi málo. Abych adresoval tento problém, vytvořil jsem víceúčelový generátor syntetických dat. Úspěšně jsem jej aplikoval jak při segmentaci tak při shlukování kolonií. Výsledné segmentační F1 skóre se mi podařilo navýšit z 0,518 na 0,729 a při shlukování jsem s využitím této segmentace dosáhl V-measure skóre 0,830. Prací navržený přístup ke generování syntetických dat nás posouvá o krok blíže k plné laboratorní automatizaci. Detailed record

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