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Microarray Data Analysis
Vogel, Ivan ; Smrž, Pavel (referee) ; Šilhavá, Jana (advisor)
The aim of this bachelor thesis is to describe the DNA microarray technology. Several analytical algorithms are discussed. It describes closely the clustering methods, especially several hierarchical clustering modifications. It gives a summary of available commercial and uncommercial software for microarray analysis. The thesis describes own implementation design of hierarchical methods. At the end, results are compared with similar uncommercial software.
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Significance of polyploidy and hybridization in evolution of European taxa of genus Arum
Podobová, Tereza ; Urfus, Tomáš (advisor) ; Hojka, Jakub (referee)
Polyploidy and hybridization are significant evolutionary trends that occur in a wide variety of plant species. This bachelor thesis includes current knowledge and data on arums with a focus on polyploidization and hybridization of the genus Arum. The change in morphology depending on the polyploidy can affect not only pollination and the associated generative reproduction. Several studies have revealed a possible correlation between ploidy levels and geographical occurrence. Hybrids are rarely described, mainly on the basis of chromosomal numbers and morphology. Rare findings of natural hybrids could be more frequent in the future with more intensive research and could have medical potential. Key words: polyploidy, hybridization, Arum, geographical occurrence, spadix
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Microarray Data Analysis
Vogel, Ivan ; Smrž, Pavel (referee) ; Šilhavá, Jana (advisor)
The aim of this bachelor thesis is to describe the DNA microarray technology. Several analytical algorithms are discussed. It describes closely the clustering methods, especially several hierarchical clustering modifications. It gives a summary of available commercial and uncommercial software for microarray analysis. The thesis describes own implementation design of hierarchical methods. At the end, results are compared with similar uncommercial software.
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