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Risk factors of atherosclerosis
Kratochvíl, Filip ; Ošťádal, Petr (advisor)
The topic of my thesis I chose based on their interest in this issues. Atherosclerosis is a multifactorial disease occurring in the vessel wall due to the interaction of metabolic and structural properties of the vessel wall , the blood components and hemodynamic forces. It's a long ongoing inflammatory process, which affects the inner wall of the damaged artery chemical, physical or biochemical effects and leads to structural changes in the vascular wall Consequently fibroproliferative inflammation. The term arteriosclerosis was first used in 1829 to describe calcifications in the wall of the artery . The term atherosclerosis was then used in 1904 to describe lipid deposits in atherosclerotic arteries. The discovery of the relationship between clinical symptoms of myocardial infarction , atherosclerosis and coronary artery thrombosis made in 1912 by James Herrick . Atherosclerosis is the process involved in pathophysiological mechanisms of organ changes , which are manifested serious complications , such as coronary heart disease, peripheral vascular disease or ischemic cerebrovascular event . Taking a number of risk factors may condition the not only atherosclerosis , but also its rapid progress and spread to other areas.
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