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The role of imaging methods and interventional radiology in liver transplantation programme: transarterial chemoembolization of hepatocellular carcinoma and therapy of vascular and biliary complications after orthotopic liver transplantation.
Laštovičková, Jarmila ; Peregrin, Jan (advisor) ; Köcher, Martin (referee) ; Hořejš, Josef (referee)
121 9. Summárý Purpose: This study was designed to evaluate the role of interventional radiology in liver transplantation programme. The aim is to present our experience, technical outcomes and long-term clinical results with chemoembolization of hepatocellular carcinoma in patients before liver transplantation and with percutaneous treatment of vascular and biliary complication after orthotopic liver transplantation. Methods: Twenty five patients (17 men, 8 women, mean age 57.76 years) with HCC were scheduled for TACE prior to liver transplantation from 2008 to 2012. Twenty three procedures were performed, 7 c-TACE in 2008 and 16 DEB TACE in next years. Thirty patients (13 men, 17 women, mean age 46.4 years) with biliary strictures after liver transplantation without endoscopic access possibility were treated with balloon dilatation and biliary duct drainage from 1996 and 2010. Twenty patients (13 men, 7 women, mean age 45.25 years) were treated with PTA/stent due to hepatic artery stenosis after liver transplantation between 1996 and 2011. Stents were placed to the hepatic/celiac artery in 16 PTAs, balloon dilatation alone was performed in 7 stenosis due to tortuosity of the vessel. Results: Liver transplantation was performed to 20 patients after TACE. Only one patient (4.5 %) was excluded from waiting...
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Škodlivé účinky konzumace alkoholu na játra a jejich funkci
Šlorová, Kamila
It is a well-known fact that an excessive consumption of alcohol has negative impact upon liver and its function. Despite this the Czech Republic, along with Russia, France and Estonia, is rated among the biggest consumers of alcohol in the world. In the Czech Republic there are only 10 % of people who abstain from drinking alcohol, and nearly 20 % of people drink alcohol at a rate that is dangerous to their health. The only solution to this is usually liver transplantation, prior to which it is recommended to wholly abstain from drinking alcohol for half a year, however, with many patients this is often not observed. The first part of the bachelor thesis deals with general information about liver, its functions, and the most frequent liver diseases. The second part of the thesis evaluates data researched in foreign literature and is divided into several main chapters: liver and alcohol, treatment of liver damaged by alcohol, and research methods.
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