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Analysis of mortality from breast cancer in selected European countries
Rathouská, Michaela ; Kučera, Tomáš (referee) ; Burcin, Boris (advisor)
Analysis of mortality from breast cancer in selected European countries Malignant neoplasms are in most European countries the second most common cause of death. The aim of this work is to describe the evolution of mortality of women which is caused by breast cancer. It describes this evolution in the years of 1980-2007 in the Czech Republic, Great Britain and Sweden. Development of mortality is set into the broader connections with a mortality rate of more frequent causes of death and certain other neoplasms in women. Work analyzes mortality by age, the incidence, and it also shows screening programs and international comparisons. Part of this work also deals with risk factors, prevention and treatment options. In all analyzed countries in analyzed period there have been decline of mortality from neoplasm, while the incidence increased. There was a shift of mortality to higher age , particularly in relation to improving health care and its increasing availability. The incidence was observed moving from the oldest to the younger age group, especially in due to introduction of the national mammography screening.
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Primary and secondary prevention of breast cancer in women
WEISSOVÁ, Veronika
Breast cancer is the most common form of cancer in female population in the Czech Republic. In 2002 the Czech Republic joined most European countries and launched nation-wide mammography screening, enabling women to attend regular preventive examinations when they reach 45 years of age. In January 2014 they started to address women to invite them for preventive breast cancer examinations, as part of a nationwide information campaign. Mortality of this cancer has been decreasing in recent years, which can be explained by the increasing quality of treatment and earlier detection of the disease. Therefore, knowledge of primary and secondary prevention is very important. The theoretical part briefly describes the anatomy of female breasts, defines a malignant tumor, as well as epidemiological aspects of breast cancer. Another chapter is about prevention itself. In the secondary prevention I describe self-examination of breasts and the history and nature of mammography screening. I also present organizations implementing preventive programs aimed at breast cancer. The practical part includes research results, which were obtained through quantitative research questionnaires. The research group consisted of women who live in the Ústí region. The questionnaire consisted of 27 questions and was answered by a group of 150 women between 18 and 44 years old and 150 women over 45 years. I handed out these questionnaires in Ústí healthcare center and I also created an electronic questionnaire which I sent across social networks. Out of the 150 (100 %) questionnaires distributed in Ústí healthcare center, I got only 60 back and 58 of them were sufficiently completed for the needs of the research, the return was only 38.7 %. I received the remaining 242 questionnaires electronically. The aim of the study was to explore the awareness of risk factors of breast cancer of women in the Ústí Region and also to find out whether women in the Ústí region carried out self-examination of breasts and if women over 45 attended regular mammography screening. Based on my research aim I set out four hypotheses. Hypothesis 1: Women in the Ústí region are informed about the risk factors of breast cancer. Hypothesis 2: Women at the age of 18 to 44 in the Usti region are more informed about the risk factors of breast cancer than women in the age group over 45. Hypothesis 3: The difference in the frequency of breast self-examination among women in the age group 18 to 44 is statistically more significant than in women in the over 45 age group. Hypothesis 4: Attending mammography examination of women over 45 in the Ústí region rises according to their level of education. The results of testing my hypotheses show that women in the Ústí region are not informed about the risk factors of breast cancer. I assumed that awareness is higher among women in the 18 to 44 age group, but even this hypothesis wasn't proven. Awareness of risk factors is on the same level in category of 18 to 44 years as in women over 45 years of age. Regarding breast self-examination, women in the above 45 years old age group carry out self-examination more often than women 18 to 44 years old. Even the last hypothesis was not confirmed, attendance of mammography doesn't appear to depend on the education of women. Awareness of women needs to increase, especially in case of risk factors of breast cancer. Awareness increase could be achieved by greater information campaign on television, in newspapers, in businesses with high numbers of working women, or in secondary and higher education through various public lectures. Over 90% of women attend Mammography screening according to my research, which are laudable results. The fact that the actual self-examination of breasts isn't carried out at all by more than half of the women in the age group 18 to 44 is serious. This work could serve as teaching or study material to improve general knowledge of this topic.
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Hazards connected with radiation exposure during a mammographic screening examination and their comparison with mammographic screening benefits.
HECHT, Ondřej
The screening mammography programme has been running succesfully in the Czech republic for 13 years. Due to its ability to uncover earlystages of breast cancer, it helps to fight this serious disease. Although the positive outcome of this programme in the Czech republic has been already proved, there is only approximately 50% of women who have been regularly treated with it.One of the major reasons for this fact is a fear of cancer induction caused by the use of X-rays during the mammography. The main goal of this thesis is to calculate the risk of breast cancer induction caused by the mammography and to compare benefits of the screening programme for a woman who goes for regular checkups and a woman who does not. The measurement of concrete doses was made in one screening centre center located in western bohemia region. The group of observed patients at the age of 45-59 was divided into three categories. The object of measurement was an average dose received during the screening mammography, plus an average dose received during an additional mammography, which may sometimes occure during the examination. These data was studied through a statistic investigation to prove that the received dose is not dependent on the patient´s age. In the theoretical part of this work main principals of the screening mammography programme and mammography itself are repeated. The methods of statistic investigation and the methodology for estimating breast cancer risks based on recommendations of ICRP Publication 103. In the practical part was proved, that the average dose received during the classical mammography does not depend on the age of the patient. This could not be proved for an additional mammography dose, because of not sufficient group of statistic data. The main hypothesis, that regular checkups using the mammographical screening programme is benefical for women , was verified.
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Risk factors importance by detection of breast carcinoma
CISÁRIKOVÁ, Štěpánka
Risk factors importance by detection of breast carcinoma Breast cancer is the most frequent women malignancy and its incidence in developed countriesis on the rise all the time. It is necessary to look for effective procedures of prevention of occurance of this desease, to examine and see all risk factors that could help, though in a small extent, to spreads this desease. It is necessary to provide very sensitive sreening, to improve all possible methods of examination and to opt for effective methods of treatment.Risk factors represent heterogenous set of impacts of both the internal and external environment and they influence an outbreak of breast cancer through various mechanisms. The goal of my work - based on analysis of risk factors - is to refer to the factors that might be important in preventive treatment of this disease. I made statistic analysis of questionaires of women with breast cancer and a group of random samples of other women. The research showed a negative impact of cancer in family ananmnesis, age of the first childbirth after the age of 30 and also the impact of the environmet - in the areas with elevated levels of radiation in the ground the braeast cancer was more frequent.Of course, my results may be burdened by small numbers mistakes but one thing is clear - that in a family history of breast cancer women should undergo a mammography screening every year. Obejctively and statistically significant results may be gained only by a long time monitoring of given number of women.
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