National Repository of Grey Literature 3 records found  Search took 0.00 seconds. 
Expanzi aktivovaných CD8+ t-lymfocytů lze výrazně zvýšit podáváním komplexů IL-2 a anit-IL-2protilátky
Tomala, Jakub ; Kovář, Marek ; Strohalm, Jiří ; Etrych, Tomáš ; Ulbrich, Karel ; Říhová, Blanka
By using the model of adoptively transferred transgenic CD8+ cells (OT-I) labeled by CFSE dye, we have measured clonal expansion, proliferation and expression of surface markers after various stimulation.We have studies prophylactic effect of complexes, alone or in combination with other cytokines, on various cancer cell lines in vivo. Our results indicate such approach is very promising and could be potent therapeutical tool in tratment of cancer
Ustanovení buněčné nádorové linie, která stabilně exprimuje zelený fluorescenční protein
Větvička, David ; Josková, Radka ; Baumgartnerová, E. ; Hovorka, Ondřej ; Ulbrich, Karel ; Říhová, Blanka
Murine T-cell lymphoma cell line EL-4 was transfected via the nucleoporation and stable transfectants have been established
Nepřímá kvantifikace jaderné akumulace doxorubicinu
Hovorka, Ondřej ; Eckschlager, T. ; Strohalm, Jiří ; Ulbrich, Karel ; Říhová, Blanka
This method increased the detection sensitivity more than ten times and allowed us to quantify doxorubicin cleaved from the conjugates and intercalated into nuclear DNA

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