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Eco-grandmother, advise! Eco-counselling in the Czech republic
Havlínová, Zuzana ; Rynda, Ivan (advisor) ; Kulich, Jiří (referee)
First part of the thesis presents foundations and purpouse of eco-counselling as a social institution in Czechoslovakia, the Czech republic and also in general. Data set consisting of queries sent to czech eco-counsellors throughout one year is described in the empirical part. It also presents in detail methods and execution of classification of more than 9 000 queries. Resulting structure is then analyzed thorou- ghly from different points of view. This synthetic and analytic process gives facts about clients' regions of interest in landscape, nature and environment protection and also everyday life. Analysis also reveals clients' true motivation and subjective or objective urge. Thus it can serve eco-counselling offices as a source material for a mid-term conception to increase its competence in environmental education. It can also be used for political and strategic decision making concerning eco-counselling in the Czech republic. Results show that majority of clients use eco-counsellor's service for ecological and environmental reasons, thus eco-counselling serves as an effective preventive en- vironmental policy instrument. Eco-counselling can be then considered to be able to decrease costs related to correction of human negative impact to environment and an effective way of decreasing...
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The metabolic pathway arginine-nitric oxide and its pharmacological modulation in acute and chronic airway diseases
Havlínová, Zuzana ; Chládek, Jaroslav (advisor) ; Anzenbacherová, Eva (referee) ; Pávek, Petr (referee)
The first part of the theses describes the changes in the metabolic pathway of arginine- nitric oxide using a model of acute lung injury (ALI) induced by bacterial lipopolysaccharide (LPS) in Wistar rats. ALI was induced by i.p. or i.t. administration of 5 mg/kg LPS (Escherichia coli, serotype O55:B5). The observational period was terminated at 3, 6 and 24 hrs following the administration. After that, the expression was studied at mRNA and protein levels of inducible and endothelial NO synthases (eNOS, iNOS), arginase 1 and 2 (ArgI, ArgI), and of cationic amino acid transporters (CAT) in lung and liver tissue, Experimental work also included the monitoring of exhaled nitric oxide (eNO) and arginine concentrations in plasma and bronchoalveolar lavage fluid (BAL). The model was further characterized by biochemical markers, the indices of alveolo- capillary membrane permeability, the presence of inflammatory cells and the concentrations of oxidative and nitrossative stress markers in the airways. After i.p. injection of LPS, a profound increase occurred in exhaled eNO and NOx concentrations in BAL and plasma. The increase in eNO was observed already in 2 hr following LPS application and its maximum was >30fold above the controls. After i.t. application, there were signs of increased oxidative stress in...
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Eco-grandmother, advise! Eco-counselling in the Czech republic
Havlínová, Zuzana ; Rynda, Ivan (advisor) ; Kulich, Jiří (referee)
First part of the thesis presents foundations and purpouse of eco-counselling as a social institution in Czechoslovakia, the Czech republic and also in general. Data set consisting of queries sent to czech eco-counsellors throughout one year is described in the empirical part. It also presents in detail methods and execution of classification of more than 9 000 queries. Resulting structure is then analyzed thorou- ghly from different points of view. This synthetic and analytic process gives facts about clients' regions of interest in landscape, nature and environment protection and also everyday life. Analysis also reveals clients' true motivation and subjective or objective urge. Thus it can serve eco-counselling offices as a source material for a mid-term conception to increase its competence in environmental education. It can also be used for political and strategic decision making concerning eco-counselling in the Czech republic. Results show that majority of clients use eco-counsellor's service for ecological and environmental reasons, thus eco-counselling serves as an effective preventive en- vironmental policy instrument. Eco-counselling can be then considered to be able to decrease costs related to correction of human negative impact to environment and an effective way of decreasing...
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