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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Entry of the Selected Company to the Foreign Market
 Drábková, Markéta ; Dlouhý, Ondřej (referee) ; Chlebovský, Vít (advisor)
Master ‘s thesis „Entry of selected company on foreign market” deals with entry of Spielberg Brno Arms s.r.o. (hereinafter referred as Spielberg Brno) to French market. The theoretical part contains the development of the internationalization of companies, includes variants of entering the foreign market and risks arising from international trade. It also characterizes individual economic analyses - PEST analysis, Porter's five forces model, SWOT analysis. The practical part focuses on the company itself, the export article and analyses. The last part of thesis proposes a concrete strategy of entry into the French market based on the analyses mentioned above.
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Donepezil ? biological activity nad evaluation of its efficiency.
 Drábková, Markéta ; Pourová, Jana (referee) ; Herink, Josef (advisor)
1 Summary Title: Donepezil - biological activity and evaluation of its efficiency Author: Markéta Drábková Supervisor: Doc. MUDr. Josef Herink, DrSc. Department: Department of biological and medicinal sciences Cognitive enhancers are drugs which preferentially affect cholinergic transmission in the central nervous system. The cholinergic system in the brain is the most seriously damaged neurotransmitter system in Alzheimer, s disease and dementia with Lewy bodies. Donepezil is a new cognitive enhancer whose mechanism of action consists of reversible specific inhibition of acetylcholinesterase activity. Donepezil increases the amount of acetylcholine available for neuron-to-neuron communication, which may relieve some memory impairment and thus prolonging of patients' self-support. Present thesis classifies cognitive enhancers, it especially describes the mechanism of action and effect of donepezil and its therapeutical usage. The principal aim of my work was to assess and evaluate the efficacy and adverse effects of donepezil from chosen clinical studies in the years 2003- 2009. The results support the conclusion that donepezil is safe and effective for long-term treatment of patients with mild or moderate Alzheimer's dementia, vascular dementia, mild cognitive impairment and multiple sclerosis. In...
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