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Study on the Mobility of Selected Representatives of Pharmaceuticals in Natural Systems
Bednárová, Paula ; Pořízka, Jaromír (referee) ; Kalina, Michal (advisor)
This diploma thesis focuses on interactions of chosen pharmaceuticals with soil and study their mobility. First part is devoted to the characteristics of the most common pharmaceuticals that appear in the environment, specifically antibacterial chemoterapeutics and analgetics. Subsequently, the occurrence of the pharmaceuticals in environment, their sources and effects are described. Further, the work focuses on soil components and soil organic matter. In conclusion of the theoretical part is the description of used analytical method for processing of the results and also the current state of the problematics. In the practical part of the thesis the experiments were made and analyzed and further served for better understanding of adsorption and interactions of chosen pharmaceuticals with soil and humin acids as the main reactive part of the soil.
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Preparation and Characterization of Iron Complexes with Amino Acids
Bednárová, Paula ; Hurčíková, Andrea (referee) ; Kalina, Michal (advisor)
This bachelor thesis focuses on the preparation and characterization of iron complexes with amino acids. The work in the theoretical part is focused on specification of iron as an essential element in living organisms, on his abilities to build complexes and on its wide range of biological attributes of these complexes, which can be natural or leading to various disorders of their metabolism. The studied literature is oriented on preparation of Fe(III) complexes with amino acids. In the experimental part of work we deal with titrational setting of zeta potential and critical aggregation concentration which were set only for amino acids L-lysine and an Aspartic acid. We also deal with coagulation reactions that had low yield in most of the selected amino acids except cystein, which doubled its amount after the modification of the conditions. We have stated that the resulting yield depends mainly on the type of used amino acid as well as on the used solvent and its amount used in synthesis.
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Study on the Mobility of Selected Representatives of Pharmaceuticals in Natural Systems
Bednárová, Paula ; Pořízka, Jaromír (referee) ; Kalina, Michal (advisor)
This diploma thesis focuses on interactions of chosen pharmaceuticals with soil and study their mobility. First part is devoted to the characteristics of the most common pharmaceuticals that appear in the environment, specifically antibacterial chemoterapeutics and analgetics. Subsequently, the occurrence of the pharmaceuticals in environment, their sources and effects are described. Further, the work focuses on soil components and soil organic matter. In conclusion of the theoretical part is the description of used analytical method for processing of the results and also the current state of the problematics. In the practical part of the thesis the experiments were made and analyzed and further served for better understanding of adsorption and interactions of chosen pharmaceuticals with soil and humin acids as the main reactive part of the soil.
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Preparation and Characterization of Iron Complexes with Amino Acids
Bednárová, Paula ; Hurčíková, Andrea (referee) ; Kalina, Michal (advisor)
This bachelor thesis focuses on the preparation and characterization of iron complexes with amino acids. The work in the theoretical part is focused on specification of iron as an essential element in living organisms, on his abilities to build complexes and on its wide range of biological attributes of these complexes, which can be natural or leading to various disorders of their metabolism. The studied literature is oriented on preparation of Fe(III) complexes with amino acids. In the experimental part of work we deal with titrational setting of zeta potential and critical aggregation concentration which were set only for amino acids L-lysine and an Aspartic acid. We also deal with coagulation reactions that had low yield in most of the selected amino acids except cystein, which doubled its amount after the modification of the conditions. We have stated that the resulting yield depends mainly on the type of used amino acid as well as on the used solvent and its amount used in synthesis.
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