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Globalisation processes and international organisations evolution: Effectivity and reform of international organisations with an example of the WTO
Procházka, Petr ; Lehmannová, Zuzana (advisor) ; Sršeň, Radim (referee)
A radical change of the socio-cultural order has brought about globalisation processes. Their consequences in the economic sphere include, mainly, growing interdependence, increasing mobility of the production factors and rising efficiency of the global economy. This brings important causes in the political dimension, were the anarchy at the global level translates into erosion of the role of state sovereignty and creation of world economy inefficiencies. Qualitatively new system of global governance, governance at multiple levels and a regulative sub-system emerge, which the World Trade Organisation is a main example of. To reach an effective solution, it is essential to introduce a reform. The central methodological bases are systems theory and neo-liberal internationalism of this analysis.
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Business plan – Advertising portal Gastrosvet.cz
Procházka, Petr ; Křížek, Miroslav (advisor) ; Kešner, Martin (referee)
The aim of this thesis is a description of the planning, establishment and development of advertising portal Gastrosvět.cz, as the actual project conducted by the Business Incubator of VŠE. The thesis is divided into theoretical and practical parts. The theoretical part explains and descibes used terms like business, businessman, SWOT analysis, balance sheet, profit and loss account, cash flow, break-point analysis, legal forms of business enterprise, life cycle of a business plan, financing options and organization structures. The practical part is concerning to the project and includes information about its business plan, staffing, know-how, the scope of the position, market segmentation, timing, legal forms, business objectives, competitive analysis, SWOT analysis before starting the project, financial planning, business strategy, requirements system, marketing and advertising, and other possibilities for the development of the project.
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HPLC determination of oximes in biological samples
PROCHÁZKA, Petr
Reactivators of acetylcholinesterase inhibited by organophosphate inhibitors play an important role in organophosphate poisoning therapy. There are a large number of reactivators being tested for their ability of penetration through blood-brain barrier (BBB) nowadays. The main aim of this thesis is to test this ability in four well know reactivators {--} HI-6, K-027, K-074 and TO-032. The 5% lethal dose (LD50) {--} therapeutic dose - of each reactivator was i.m. (intramuscularly) applied to experimental animals (Wistar rats) into right posterior thighs. Then the animals were sacrificed and the blood (plasma) and brain were collected for HPLC analysis. Subsequently, brain and plasma were frozen at -80 °C and stored until the assay. The reactivator concentrations were measured in plasma and four parts of the brain {--} frontal cortex (FC), basal ganglia (BG), ponto-medullar part (PM) and cerebellum (Ce). There were five animals for each group used for the purpose of the experiment. The concentrations of reactivators in plasma and blood samples were measured using HPLC-UV/VIS methodology. HI-6 concentrations CFC were on the average 4.29% of Caverage in plasma, CBG were on the average 1.9% of Caverage in plasma, CPM were on the average 2.3% of Caverage in plasma, and CCe were on the average 1.85% of Caverage in plasma. These rates were counted from all concentrations within the scope of particular observed parts of the brain. All the other tested reactivators were not quantified in brain at all.
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