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Interactive Gantt Charts
Skalický, Tomáš ; Vojtáš, Peter (referee) ; Barták, Roman (advisor)
This work deals with problems of interactive rescheduling in Gantt charts. The goal of the work is to design and implement an algorithm which resolves the inconsistencies in a schedule. First existing approaches are studied. Algorithm for solving our inconsistencies in a schedule is the most important contribution of this work. It is introduced there and there is also it's proof of correctness and finiteness. Demonstration of applicability of the algorithm follows. For this reason, program GanttViewer which is a part of this work is used. Finally, this program is described in detail.
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Design of user interface and implementation of application for test execution in TestLink
Skalický, Tomáš ; Buchalcevová, Alena (advisor) ; Veselka, Marcel (referee)
The goal of this thesis is to design a user interface and to implement an application that is used for test execution in test management tool TestLink. This application is designed to streamline and simplify the process of test execution in this tool. The theoretical part of the thesis describes features and the interface of TestLink and compares it with other similar tools. The practical part is focused on analysis, user interface design, and implementation of the application. The outcome of this thesis is in addition to the application itself also a library written in PHP, which is used for communication with the application programming interface of TestLink and which simplifies the creation of similar applications.
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Paratrypanosoma is a novel early-branching trypanosomatid
SKALICKÝ, Tomáš
The kinetoplastids are a widespread and important group of single-celled eukaryotes, many of which are devastating parasites of animals, including humans. We have discovered a new insect trypanosomatid in the gut of Culex pipiens mosquitoes. Glyceraldehyde-3-phosphate dehydrogenase- and SSU rRNA-based phylogenetic analyses show this parasite to constitute a distinct branch between the free-living Bodo saltans and the obligatory parasitic clades represented by the genus Trypanosoma and other trypanosomatids. From draft genome sequence data, we identified 114 protein genes shared among the new flagellate, 15 trypanosomatid species, B. saltans, and the heterolobosean Naegleria gruberi, as well as 129 protein genes shared with the basal kinetoplastid Perkinsela sp. Individual protein phylogenies together with analyses of concatenated alignments show that the new species, here named Paratrypanosoma confusum n. gen., n. sp., branches with very high support at the base of the family Trypanosomatidae. P. confusum thus represents a long-sought-after missing link between the ancestral free-living bodonids and the derived parasitic trypanosomatids. Further analysis of the P. confusum genome should provide insight into the emergence of parasitism in the medically important trypanosomatids.
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Consumer credits and tools used for their comparison
Skalický, Tomáš ; Půlpánová, Stanislava (advisor)
This bachelor thesis deals with consumer credits. It aims to familiarize potential applicant for the consumer credit with fundamental information and facts which are necessary for orientation in these broad problems. At the beginning, new law, which came into force in January 2011, is analyzed in detail. That is followed by an introduction of methods of classification of consumer credits with emphasis on mutual differences between particular types. Principal part focuses on methods of assessing and comparison of advantages of consumer credits by means of interest rate, rate of increase and annual percentage rate of costs. Finally, particular bank and non-bank credit offers are compared by using above mentioned tools of evaluation of the profitability of credits.
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Functional analysis of Ssc1 and Iba57 proteins in \kur{Trypanosoma brucei}
SKALICKÝ, Tomáš
Aim of this thesis was to shed light on the function(s) of Iba57 and Ssc1 proteins in both life cycle stages of T. brucei using RNA interference. Depletion of Ssc1 resulted in severe grow phenotype, decrease in activities of iron-sulphur cluster-containing enzyme aconitase but no increase in oxidative stress sensitivity or accumulation of ROS in mitochondrion. Down regulation of Iba57, specialized maturation factor of aconitase and homoaconitase, lead to depletion of aconitase, destabilization of Isa1 and increased sensitivity to oxidative stress and accumulation of ROS in both stages.
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