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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Role of Zinc-α2-glycoprotein in tumors
 Kotvalová, Hanka ; Šmahel, Michal (advisor) ; Kubů, Martin (referee)
The Zinc-α2-glycoprotein (ZAG) encoded by the AZGP1 gene particularly contributes to the regulation of lipid and glucose metabolism. In different types of tumors, its altered production was found and the association of the ZAG level with the patient's prognosis was suggested. However, the role of ZAG in tumor progression can differ in individual malignancy types and mechanisms of ZAG function are not sufficiently identified. The objectives of the bachelor's thesis are a description of the structure of the ZAG protein and the regulation of AZGP1 expression, a summary of the identified ZAG functions in nonmalignant diseases, and a focus on the role of ZAG in tumors, particularly on the mechanisms of its action and its potential use as a biomarker.
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Víno jako účinná prevence a lék vůči srdečním chorobám
 Brzobohatá, Anna
Positive effects of abstemious wine consummation are currently an increasingly discussed topic. They are especially indisputable in the area of cardiovascular health. There exist great many of unqualified and ill-founded articles regarding this subject matter. The Bachelor thesis elaborates on several dozens of academic papers dealing with effects of wine consummation on medication and prevention of heart and, related to some extent, vascular diseases. It elucidates differencies between white and red wine activity, includes recommendations about prosperous, periodically consumed wine capacity that differs with women and men, and introduces briefly the most significant heart diseases and substances contained in wine that give it his beneficial virtues.
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