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National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Comparison of the histochemical results of estrogen and progesterone receptors in the breast, ovaries or uterus tumours.
 Urbanová, Štěpánka ; Kovařík, Miroslav (advisor) ; Dvořák, Josef (referee)
6 1.2. Souhrn v anglickém jazyce This thesis deals with usage of cell tumour markers for identification of appropriate treatment of breast carcinoma. We focused primarily on the dependence of marker values on pantients' age. The theoretical part of the thesis contains all theory necessary for the practical part. First, we explained the definition of tumour markers and especially we described so called cell markers, i.e. ER, PR and HER2/neu which we examined in the practical part. Then we described the recommended treatment in dependence on marker values. Subsequently there is a description of methods for taking of cancer tissue for analysis because samples tested in the practical part are taken by different methods. In the end we described basics of testing of statistical significance and especially Wilcoxon rank-sum test. In the practical part we analysed the values of cell markers of tissues which were taken in a hospital in Jihlava between 2000 and 2007. First we checked development of the results during the time (since the foundation of the lab). With respect to the fact that the results differed depending on the used chemicals, we used for the subsequent analysis data from a reduced time period in which the results were most stable. Then we used those data for the analysis of dependence of markers on...
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