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Information System Selection
Hanák, Petr ; Procházka, Vít (referee) ; Neuwirth, Bernard (advisor)
Bachelor thesis deals with the selection of the information system for the selected copany. The work includes regular processes of the company and analysis of the status of the company. There are also explored business requirements and from requirement chosen an appropriate information system. For optimum solution were exploited consultation with the entire staff of the company and tutor.
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Mathematical model for Transportation Problem in Waste Management
Procházka, Vít ; Touš, Michal (referee) ; Pavlas, Martin (advisor)
This bachelor's thesis deals with the development of the mathematical model of transportation problem in waste management, which is used for analysis of current issue of mixed municipal waste treatment in the Czech Republic. The theoretical part of thesis aims to introduce basic terms of graph theory and optimization with the focus on linear programming. The second part aims to development of the model and its implementation to GAMS. And next, the post-processing of results is shown, vizualization in ArcGIS included.
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Modulations in PLC systems
Procházka, Vít ; Kouřil, Jiří (referee) ; Krajsa, Ondřej (advisor)
The bachelor thesis describes principles and methods of Powerline Communications, practical usage possibilities both in industrial applications but mainly in broadband systems that may represent promising competition to conventional broadband access, e. g. xDSL connections without the need of new wiring, WIFI etc. The thesis also focuses on problems that can occur in the communication channel from the view of electromagnetic compatibility and assorted interferences. The 50 Hz frequency electric network (60 Hz in the USA) was not designed for data signal transmission, problems may arise mainly at higher frequencies and broadband communication. It is necessary to implement methods which enable transfer of information signal through a communication channel with minimalization of problems such as interference, cable attenuation, electromagnetic compatibility, bit error rate (BER), etc. Furthermore, currently used modulation principles and their characteristics are described, such as spread spectrum modulation DSSS, FHSS, traditional OFDM, alternative modulations FMT and DWMT with filter banks. The last chapter of the bachelor thesis features models of particular modulations created in the Matlab-Simulink program and the conclusion presents advantages and disadvantages of their implementation in PLC systems.
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Modelling of PLC system to ensure the reliability of communication
Procházka, Vít ; Mišurec, Jiří (referee) ; Mlýnek, Petr (advisor)
The master´s thesis is focussed on principles and characteristics of Powerline Communications (PLC), practical usage possibilities and advantages and disadvantage of it. There are described mudulations and a channel encoding which are in PLC used. The main part of the thesis deals with a design of a channel as transfer function through the use of two methods, an echo model and the ABCD matrix. After finishing of the design of transfer function the model of communication was created in the Matlab-Simulink program. There were used the narrowband modulations in the model and analyzed the bit error rate of the tranfer data. In the end all results were treated graphically and evaluated.
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Cancer metabolism and its role in the sensitivity to ASNase of leukemic cells to L-asparaginase
Alquezar Artieda, Natividad ; Starková, Júlia (advisor) ; Procházka, Vít (referee) ; Truksa, Jaroslav (referee)
Cancer metabolism and its role in the sensitivity of leukemic cells to L- asparaginase ABSTRACT No ultimate treatment strategy exists for relapsed or non-responsive (15-20%) children with acute lymphoblastic leukemia (ALL). In this study, we aimed to elucidate the impact of metabolic rewiring in leukemic cells on poor therapy response and the emergence of resistance. This dissertation focuses on l-asparaginase (ASNase), a crucial chemotherapeutic agent and its effect on leukemia, using models of leukemic cell lines and primary cells of ALL patients. Cell metabolism was assessed by measuring metabolic pathways and nutrient influx using a Seahorse analyzer and stable isotope tracing. Main findings of the study demonstrated that the ASNase- therapy response was mitigated by the activity of the mechanistic target of rapamycin (mTOR)- regulated biosynthetic pathways. This phenomenon was induced by the bone marrow environment, which enabled the activation of the resistant mechanism in leukemic cells. We next found a correlation between the following metabolic features and lower sensitivity to ASNase: low ATP- linked respiration, high mitochondrial membrane potential and high glycolytic flux before therapy. The latter was shown to have prognostic implications. Moreover, high glycolytic flux was detected in T-ALL...
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Optimization of Value at Risk using integer programming
Fausek, Matěj ; Branda, Martin (advisor) ; Procházka, Vít (referee)
This thesis is focused on the portfolio optimization problem. The foundations of this problem were laid by Professor Markowitz (1952), who measured risk using the standard deviation of random returns. In this paper, the standard deviation will be replaced by the Value at Risk function. We will show that if the number of past observations or the number of assets is limited by a constant, there will be an algorithm that can solve the problem in a reasonable amount of time. We will formulate the problem as a mixed-integer linear optimization problem. This paper also includes computation on real data. 27
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Optimalizace plánování tras a rozvrhů svozu odpadu
Loub, Pavel ; Procházka, Vít (advisor) ; Branda, Martin (referee)
This thesis proposes a mixed integer linear program for waste collection in South Moravian region. For deterministic models are difficult to solve by exact methods, it was necessary to find a way to obtain solutions in reasonable time. Hence, a brand new metaheuristic based on Simulated annealing is developed for solving the waste collection problem. 1
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Stochastic multistage problems for drug transportation
Tekulová, Paula ; Kopa, Miloš (advisor) ; Procházka, Vít (referee)
This thesis deals with the multi-stage stochastic problems for drug distribu- tion. In the first chapter, we introduced two-stage and multi-stage stochastic programming problems. In the second chapter, we constructed a scenario tree and introduced two methods on how to generate scenarios - the moment method and paths-based methods. In the third chapter, the transportation problem is formulated. Next, we introduced two-stage and multi-stage models, which aim to maximize the profit of pharmacies. The multi-stage models are then extended with probability constraints. In the practical part, we analyzed the historical data and eliminated the seasonality component. Then, we generated scenarios and constructed scenario trees. Lastly, we analyzed the results of the models. 1
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Modelling of the waste flow in the Czech Republic
Němcová, Lucie ; Procházka, Vít (referee) ; Šomplák, Radovan (advisor)
Strategic planning is the basis for efficient and sustainable waste management. Data collection and its deep understanding are essential for effective planning. Waste flows are an important information to assess waste management to date. This information has so far been available only aggregated at national level in the Czech Republic. In this thesis, an approach has been developed to reconstruct the waste flows at a sub-national level from available data. The approach consists of two optimization models: partial and final. The partial model is based on expert assumptions. The reconstruction of the flows by the partial model is done sequentially in smaller groups of flows. The computation of the partial model is repeated with different composition of the groups of flows optimized at the same time. Each iteration results in a~candidate solution which is used as an input data for the final model. The solution of the final model yields the final reconstruction of the waste flows. Model development and testing was carried out on problems simulated based on the real data from the waste management of the Czech Republic.
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