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Assessment of diffusion coefficient
Mikeš, Petr ; Schimmel, Jiří (referee) ; Míča, Ivan (advisor)
Most acoustic measurements and parameters provided by a manufacturer of acoustic elements, which are offering additional solutions to room acoustics as well as acoustic construction works, are mainly limited to the parameters associated with absorption of individual elements. Until now, these diffusional elements have been neglected. Diffusi- onal panels are used to e.g. eliminate direct reflection of sound waves to the listener or reflection of sound waves concentrated at one point. Combination of absorptive acoustic panels and diffusion elements results in a space that is customised to the submitter’s needs.
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Statical acoustical sources localization
Mikeš, Petr ; Holešinský, Pavel (referee) ; Míča, Ivan (advisor)
The microphone array can be used in many important applications. The primary usage, which most of other applications are based on, is only: acoustic sources localization and separation of each signal from their compound. The microphone array is usually included in ordinary mobile phones, where it reduces noise and sound of its surrounding that otherwise degrades vocal speech. Other microphone array utilization is in for example speech identification, speakers’ localization or signal isolation of one speaker.
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Exctretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene
Mikeš, Petr ; Mráz, Jaroslav (referee)
Adenine adducts of styrene : 3-(2-hydroxy-1-phenylethyl)adenine (N3αA) and 3-(2-hydroxy-2- phenylethyl) adenine (N3βA), were found in the urine of mice exposed to styrene vapor. Vast majority of styrene is metabolized to styrene -7,8-oxide. This reactive molecule is futher bio transferred either to mandelic and phenylglyoxalic acid or bounds to nucleophilic sites in biomolecules. Adducts of styrene oxide with amino acids contained in proteins and with purine and pyrimidine bases of nucleic acid were observed during in vitro tests. These styrene-7,8-oxide derived adenine adducts, as well as previously identified guanine adducts, 7-(2-hydroxy- 1- phenylethyl)guanine (N7αG) and 7-(2-hydroxy-2-phenylethyl)guanine (N7βG) were quantified by HPLC-ESI-MS2 and the excretion profile during and after repeated exposure to 600 mg.m-3 or 1200 mg m-3 of styrene for 10 consecutive days (6 h/day) was determined. The excretion was dose dependent. Total excreted amount of N3 adenine adducts (N3αA+N3βA) represents 0.8 ×10−5 % of the absorbed dose, while overall sum of N7 guanine adducts (N7αG+N7βG) yields about 1.4 ×10−5 % of the dose. No accumulation of the adducts was observed. Due to rapid depurination of the DNA, the excretion of both N3 adenine and N7 guanine adducts ceased shortly after finishing the exposure. Both N3...
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Spread of International Law into Decision-Making Practice of Domestic Authorities
Mikeš, Petr
1 Abstract Spread of International Law into Decision-Making Practice of Domestic Authorities In principle international law does not impose its subjects how to achieve compliance with its international legal obligations within their jurisdiction. However, for the effectiveness of international law in each country it is the approach of legislative, executive and judiciary authorities to international obligations that is vital. The thesis focuses mainly on the judiciary, while the issues of international law application by the domestic courts have not yet been at full length described. Part One is an introduction which describes the subject of the work methodology and terminology used in its processing. The first main aim of the thesis was to examine in detail legal rules for the application of international law as they result from both constitutional and ordinary law. These rules constitute a framework within which institutions applying international law deal with it. The third part of the thesis is mainly dedicated to fulfilment of the first main aim, it is entitled The Current Application of International Law by National Authorities of the Independent Czech Republic and the Development of this Legislation. But partially also the second part, entitled Historical Development of Binding Force of International...
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Spread of International Law into Decision-Making Practice of Domestic Authorities
Mikeš, Petr ; Šturma, Pavel (advisor) ; Balaš, Vladimír (referee) ; Týč, Vladimír (referee)
1 Abstract Spread of International Law into Decision-Making Practice of Domestic Authorities In principle international law does not impose its subjects how to achieve compliance with its international legal obligations within their jurisdiction. However, for the effectiveness of international law in each country it is the approach of legislative, executive and judiciary authorities to international obligations that is vital. The thesis focuses mainly on the judiciary, while the issues of international law application by the domestic courts have not yet been at full length described. Part One is an introduction which describes the subject of the work methodology and terminology used in its processing. The first main aim of the thesis was to examine in detail legal rules for the application of international law as they result from both constitutional and ordinary law. These rules constitute a framework within which institutions applying international law deal with it. The third part of the thesis is mainly dedicated to fulfilment of the first main aim, it is entitled The Current Application of International Law by National Authorities of the Independent Czech Republic and the Development of this Legislation. But partially also the second part, entitled Historical Development of Binding Force of International...
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Exctretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene
Mikeš, Petr ; Mráz, Jaroslav (referee)
Adenine adducts of styrene : 3-(2-hydroxy-1-phenylethyl)adenine (N3αA) and 3-(2-hydroxy-2- phenylethyl) adenine (N3βA), were found in the urine of mice exposed to styrene vapor. Vast majority of styrene is metabolized to styrene -7,8-oxide. This reactive molecule is futher bio transferred either to mandelic and phenylglyoxalic acid or bounds to nucleophilic sites in biomolecules. Adducts of styrene oxide with amino acids contained in proteins and with purine and pyrimidine bases of nucleic acid were observed during in vitro tests. These styrene-7,8-oxide derived adenine adducts, as well as previously identified guanine adducts, 7-(2-hydroxy- 1- phenylethyl)guanine (N7αG) and 7-(2-hydroxy-2-phenylethyl)guanine (N7βG) were quantified by HPLC-ESI-MS2 and the excretion profile during and after repeated exposure to 600 mg.m-3 or 1200 mg m-3 of styrene for 10 consecutive days (6 h/day) was determined. The excretion was dose dependent. Total excreted amount of N3 adenine adducts (N3αA+N3βA) represents 0.8 ×10−5 % of the absorbed dose, while overall sum of N7 guanine adducts (N7αG+N7βG) yields about 1.4 ×10−5 % of the dose. No accumulation of the adducts was observed. Due to rapid depurination of the DNA, the excretion of both N3 adenine and N7 guanine adducts ceased shortly after finishing the exposure. Both N3...
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The creation of training methodology for medical personnel to operation the lung ventilator with utilization of trequently asked questions
Zdráhal, Vojtěch ; Otáhal, Michal (advisor) ; Mikeš, Petr (referee)
The goal of this Diploma thesis is to consolidate questions asked during the training of medical personnel for the correct usage of the lung ventilator Hamilton Medical G5, and to create more effective training methodology to safely operate this unit, based on collected inquiries. The training for this concrete device is assumed to be valid for at least 10 years. The practical utilization of the thesis is for the exclusive distributor of devices of this brand and also for technical departments of hospitals where the unit is installed in. The theoretical part of the thesis cosists of a legislative scope, which defines the issue of training, the training process itself and a basic description of the lung ventilator. Practical part consists of training methodology for effective and safe usage of the lung ventilator Hamilton Medical G5, based on collected inquiries. It is divided into two basic parts with an emphasis on issues related to medical personnel at first, and then to the issues oriented more to doctors.
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Statical acoustical sources localization
Mikeš, Petr ; Holešinský, Pavel (referee) ; Míča, Ivan (advisor)
The microphone array can be used in many important applications. The primary usage, which most of other applications are based on, is only: acoustic sources localization and separation of each signal from their compound. The microphone array is usually included in ordinary mobile phones, where it reduces noise and sound of its surrounding that otherwise degrades vocal speech. Other microphone array utilization is in for example speech identification, speakers’ localization or signal isolation of one speaker.
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Assessment of diffusion coefficient
Mikeš, Petr ; Schimmel, Jiří (referee) ; Míča, Ivan (advisor)
Most acoustic measurements and parameters provided by a manufacturer of acoustic elements, which are offering additional solutions to room acoustics as well as acoustic construction works, are mainly limited to the parameters associated with absorption of individual elements. Until now, these diffusional elements have been neglected. Diffusi- onal panels are used to e.g. eliminate direct reflection of sound waves to the listener or reflection of sound waves concentrated at one point. Combination of absorptive acoustic panels and diffusion elements results in a space that is customised to the submitter’s needs.
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OpenWrt
MIKEŠ, Petr
Thesis contains basic information about operating system OpenWrt. The first part is devoted to the history and development of this system. The work includes a description of the installation of the selected device and its settings. The thesis also includes comparative tests carried out in comparison with the original operating system router. The reader can decide which system is better suited to its needs.
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