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Scientific literature with the theme of insects in the practice of kindergarten
Faltusová, Kateřina ; Laufková, Veronika (advisor) ; Kadrnožková, Monika (referee)
This master's thesis entitled "Utilization of educational literature on the topic of insects in the practice of preschool education" is divided into theoretical and empirical sections. The aim of the thesis is the development of scientific knowledge through the use of children's educational literature in the preschool environment. The theoretical section outlines the characteristics of preschool-aged children with respect to the topic of the thesis, issues related to environmental education in preschool education, characteristics of literature for children, utilization of educational books in preschools, and an analysis of the Framework Educational Program for Preschool Education in relation to the thesis topic. The objective of the empirical section is to create lessons using educational literature about insects that contribute to the development of scientific skills in children. Additionally, it seeks to determine the popularity of educational books about insects based on the age and gender of the children, as well as to map the reading environment of the children. The results of the practical part were verified based on pretest and posttest, participant observation of children, a questionnaire for parents of pupils, and activities aimed at assessing the popularity of books. The action research...
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Vitamins and dietary supplements in the nutrition of patients with hematopoietic disorders
Chmelařová, Elen ; Dusílková, Nina Borisovna (advisor) ; Faltusová, Kateřina (referee)
This bachelor's thesis deals with the possible beneficial effects of vitamins, minerals and dietary supplements that could positively influence the course of treatment of blood cancers. In addition to vitamins and minerals, dietary supplements for the purposes of this thesis include various food supplements that can be purchased in pharmacies, as well as foods or spices, herbs and mushrooms that can be purchased in regular grocery stores. The main objective of the study was to find out whether patients take any of these selected supplements during treatment. The secondary aim of this work was to get an idea about the patients' awareness, their choice of food supplements that they purchase and how they themselves evaluate the effect of these supplements on their health status. The theoretical part deals with the brief characteristics of the most common haemato- oncological diseases of patients visiting the specialist departments of the General Faculty Hospital in Prague (VFN). In the theoretical part, this thesis also deals with a total of 57 different supplements (9 vitamins, 6 minerals, 15 food supplements and 27 different foods, spices, herbs and mushrooms) that could have positive effects in the treatment of these serious diseases, as reported in the scientific literature and also in the popular...
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Molecular mechanisms of sterile inflammation in damaged hematopoietic tissue
Čiháková, Zuzana ; Faltusová, Kateřina (advisor) ; Bačová, Barbora (referee)
Hematopoietic tissue is home to hematopoietic stem cells (HSCs), which continuously generate all blood and immune cells. Tissue damage or cellular stress can lead to sterile inflammation. In response to the sterile inflammation, HSCs are activated to proliferate and switch to emergency hematopoiesis. Long-term exposure of hematopoietic tissue to inflammatory signals leads to increased differentiation at the expense of self-renewal of HSCs, DNA damage, and genetic instability, which can lead to cell death, permanent bone marrow damage and hematopoietic damage.
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The role of stem and progenitor cells in regeneration of hematopoietic tissue
Faltusová, Kateřina ; Nečas, Emanuel (advisor) ; Hofer, Michal (referee) ; Filipp, Dominik (referee)
Tissue regeneration is a complex and highly orchestrated process dependent on cells with the potential to restore structures and functions and on controlling factors from the tissue microenvironment. Hematopoietic tissue has a high ability to regenerate, which is attributed to the presence of stem cells, but the regeneration of severely damaged adult tissue is still only partially understood. Hematopoietic tissue provides a unique opportunity to study tissue regeneration due to its well-established steady- state structure and function, easy accessibility, advanced research methods, and well-defined embryonic, fetal, and adult stages of development. Embryonic/fetal liver hematopoiesis and adult hematopoiesis recovering from damage share the needto expand populations of progenitors and stem cells in parallel with increasing production of mature blood cells. We analyzed adult hematopoiesis in mice subjected to a submyeloablative dose (6 Gy) of gamma radiation, in which only a few cells with reconstituting capacity survived. We targeted the period of regeneration characterized by the renewed massive production of mature blood cells and the ongoing expansion of immature hematopoietic cells. Cells from the top of the hematopoietic hierarchy, hematopoietic stem cells, and multipotent progenitors are almost missing...
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