|
|
The concept of the ideal of beauty in relation to physical health among students of multi-year gymnasium
Dušková, Anna ; Machovcová, Kateřina (advisor) ; Kočí, Jana (referee)
This bachelor's thesis deals with the issue of beauty ideal in relation to physical health among students of multi-year gymnasium. The aim is to understand how the girls of a given gymnasium perceive this issue and in what context this circumstance affects them. Another aim is to find out the awareness of school representatives and their understanding of girls with self- image or eating disorders. The theoretical part focuses on the adolescent period in different areas from nutrition through body image to anorexia nervosa. The empirical part of the thesis uses qualitative research and a case study design. Group discussion was used as a method of data collection, and two discussions were held. One involved discussion with the girls and the other with school representatives. Thus, the research sample represents girls of a multi-year gymnasium, specifically thirds and fourths classes (ranging in age from 13-15 years) and representatives of the school. The research also included an analysis of school documents such as the School Curriculum and the Annual Report for the last school year. The data collected was then analyzed using open coding, and three categories were evaluated. The research shows that the female students have a rational view of a healthy and beautiful body, but their own perception of...
|
|
|
Synthesis of thiazolidine-2,4-dione derivatives as potential drugs I
Dušková, Anna ; Kučerová, Marta (advisor) ; Zitko, Jan (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Title of diploma thesis: Synthesis of thiazolidine-2,4-dione derivatives as potential drugs I Student: Anna Dušková Supervisor: PharmDr. Marta Kučerová, Ph.D. The theoretical part of this diploma thesis summarizes the biological activity of thiazolidine- 2,4-dione derivatives, focused mainly on their antibacterial, antimycobacterial and antifungal effects. The theoretical part shows that thiazolidine-2,4-dione derivatives are substances that have great potential to become good candidates for new drugs that are needed to be obtained due to the growing bacterial resistance to existing drugs. Thiazolidine-2,4-dione derivatives are already used in clinical practice as oral antidiabetics - pioglitazone and rosiglitazone. In the experimental part, I dealt with a three-step synthesis of (2,4-dioxothiazolidin-3-yl) acetic acid derivatives, which, however, was not succesful to prepare except for one product. This was followed by the synthesis of thiazolidine-2,4-dione derivatives, which consisted of the Knoevenagel condensation of thiazolidine-2,4-dione with aromatic and heterocyclic aldehydes, in which we managed to obtain a total of eight products. All substances were characterized...
|
|
|
Synthesis of thiazolidine-2,4-dione derivatives as potential drugs I
Dušková, Anna ; Kučerová, Marta (advisor) ; Zitko, Jan (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Pharmaceutical Analysis Title of diploma thesis: Synthesis of thiazolidine-2,4-dione derivatives as potential drugs I Student: Anna Dušková Supervisor: PharmDr. Marta Kučerová, Ph.D. The theoretical part of this diploma thesis summarizes the biological activity of thiazolidine- 2,4-dione derivatives, focused mainly on their antibacterial, antimycobacterial and antifungal effects. The theoretical part shows that thiazolidine-2,4-dione derivatives are substances that have great potential to become good candidates for new drugs that are needed to be obtained due to the growing bacterial resistance to existing drugs. Thiazolidine-2,4-dione derivatives are already used in clinical practice as oral antidiabetics - pioglitazone and rosiglitazone. In the experimental part, I dealt with a three-step synthesis of (2,4-dioxothiazolidin-3-yl) acetic acid derivatives, which, however, was not succesful to prepare except for one product. This was followed by the synthesis of thiazolidine-2,4-dione derivatives, which consisted of the Knoevenagel condensation of thiazolidine-2,4-dione with aromatic and heterocyclic aldehydes, in which we managed to obtain a total of eight products. All substances were characterized...
|
|
| |
guest ::
RSS feed.