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National Repository of Grey Literature 3 records found  Search took 0.00 seconds. 
Information System Selection
 Plojhar, Jan ; Šamal, Vladimír (referee) ; Koch, Miloš (advisor)
The bachelor thesis focuses on finding the best suiting solution of the information system for a concrete production company. In the theoretical part of the bachelor thesis there are the basic concepts pointed out and described the methodology of choosing the information system. The solutions of different suppliers are analyzed according to a specifically chosen criteria and one of the solutions is chosen at the end.
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Treatment of neurogenic detrusor overactivity using botulinum toxin A
 Šámal, Vladimír ; Morávek, Petr (advisor) ; Zachoval, Roman (referee) ; Krhut, Jan (referee)
2. Summary Treatment of neurogenic detrusor overactivity using botulinum toxin A Introduction: The treatment of neurogenic detrusor overactivity (NDO) is still a serious medical, social and economic problem. Using onabotulinumtoxinA (onaBTA) is the first choice in patients who are refractory to standard anticholinergic therapy or with the occurrence of serious adverse events from this treatment. The standard way of applying onaBTA is intramural injection into the detrusor of the urinary bladder. Aim: To evaluate the effectiveness of the NDO treatment with submucosal applications of onaBTA with regard to the complex mechanism of the action of onaBTA on the urinary bladder. Methods: A randomized, prospective open-label study was performed. The study population consisted of patients with neurogenic detrusor overactivity due to spinal cord injury. A total of 23 patients, in which urinary incontinence persisted due to NDO despite anticholinergic therapy, were included. After randomization, patients were treated with 300 U onaBTA applied in 30 injection sites, sparing bladder trigone. In group A the treatment was carried out using submucosal applications and in group B with intramural application into the detrusor. The length of the study was 12 weeks. Urodynamic examination was performed before and after the...
Detailed record
Information System Selection
 Plojhar, Jan ; Šamal, Vladimír (referee) ; Koch, Miloš (advisor)
The bachelor thesis focuses on finding the best suiting solution of the information system for a concrete production company. In the theoretical part of the bachelor thesis there are the basic concepts pointed out and described the methodology of choosing the information system. The solutions of different suppliers are analyzed according to a specifically chosen criteria and one of the solutions is chosen at the end.
Detailed record

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