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Bioassay Guided Separation of Metabolites of the Selected Plant Species - Evolvulus Alsinoides
Červenka, František ; Jahodář, Luděk (advisor) ; Grančai, Daniel (referee) ; Patočka, Jiří (referee)
9. SUMMARY 134 This experimental work deals with pharmaco-botanical evaluation of the aerial part of taxon Evolvulus alsinoides L. The plant is a component of formulations with nootropic and adaptogenic activity. A subject of the investigation was a dried herb of the plant, which is of Indian origin. The aim of this work was to extend the knowledge about compounds of the taxon, to evaluate biological activity of the fractions, isolated substances and to determine characteristic metabolites of the plant. In the first part of the project the crude extract of the plant E. alsinoides was prepared by percolation of 8.8 kg of herb with 95% ethanol. The extract was partitioned into three extracts by extracting by two solvents of different polarity (petroleum ether, ether). The first fraction of weight 92.1 g was obtained by extracting of methanolic solution of crude extract with petroleum ether. The second fraction of weight 69.7 g was obtained by extracting of water solution of the crude extract with ether. The remaining solvent was evaporated from the crude extract and this one represented the third part - polar residue, yield 231 g. The fractions were processed by the methods of column chromatography (CC). The bioassay-guided separation of selected parts of extract (test of acute toxicity, fototoxicity,...
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Investment controlling and its application in a particular company
Kotásková, Martina ; Král, Bohumil (advisor) ; Červenka, František (referee)
The diploma thesis "Investment controlling and its application in a particular company" focuses on principle features of investment controllership and its application in practice. The theoretical part summarizes theoretical knowledge of the field of the investment decision-making and investment controllership. Attention is devoted specially to basic terms and methods used in this field. The practical part deals with analyses of recent stage of investment controllership usage in the ABC, s. r. o. company. According to project results the advantages and insufficiencies of recent stage are evaluated including suggestions for future improvements.
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