National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Technical aspects of aortic root sparing surgery:Structural changes occurring during different thawingprotocols of cryopreserved human aortic root allografts and thereproducibility of external aortic root annuloplasty using Coroneo ring.
Novotný, Róbert ; Hlubocký, Jaroslav (advisor) ; Vojáček, Jan (referee) ; Pirk, Jan (referee)
Aortic valve-sparing procedures treating patients with aortic root aneurysm with or without aortic insufficiency and patients with ascending aortic aneurysm and aortic insufficiency are no longer experimental and unproven procedures. A successful aortic valve-sparing or repair operation aims not only to correct the failing part of the aortic root but also to restore the intro- and the inter-component relationship of the aortic root elements to optimal dimensions and relations. The avoidance of anticoagulation therapy and prosthesis-related complications makes aortic valve repair a tempting procedure. Considering the increasing rate of cusp repair reported in scientific literature, conservative aortic valve surgery seems to be developing into aortic valve repair surgery. This Dissertation Theses are devoted to the study of some specific technical aspects of aortic root sparing surgery, namely to the study of structural changes occurring in cryopreserved human aortic root allografts and the reproducibility of Coroneo ring implantation procedure. The Introduction of these Dissertation Theses deals with the general review of aortic valve- sparing operations in the light of the historical aspects of used surgical technique, dynamic anatomy and the current situation. One part of the Introduction is...
Mechanical properties of mitral allografts
Hlubocký, Jaroslav ; Špatenka, Jaroslav (advisor) ; Dominik, Jan (referee) ; Rosenberg, Josef (referee)
Mitral allograft has never been as widely used as the aortic one for the treatment of infective endocarditis in clinical practice. Results of mitral valve replacements with mitral allograft were poor. Development of better techniques of mitral valve repair and improving quality of valve prostheses led surgeons to abandon use of mitral allografts in mitral position. On the other hand that technique could be helpful for treatment of tricuspid valve pathology, mainly of infectious endocarditis. We were evaluating the possibility of inserting a cryopreserved mitral allograft into the tricuspid position in a sheep experimental model. Within the framework of this experimental project the mechanical properties of the cryopreserved mitral allograft were tested. A novel methodology of graft tissue mechanical properties testing was developed. It reflexes the surgical technique of mitral allograft transplantation as it investigates whole functional unit composed of mitral annulus, leaflet, chordae tendinaea, and papillary muscle together. A five-parameter Maxwell model was applied to characterize the viscoelastic behavior of sheep mitral valves. A control group of 39 fresh mitral specimens and a test group of 13 cryopreserved mitral allografts processed according to the tissue bank standards were tested. The testing...

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