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Use of Fenton Reaction for Drug Degradation in the Ecosystem
Tomešová, Lenka ; Smrček, Stanislav (advisor) ; Břichnáčová Habartová, Věra (referee)
The elimination of unwanted substances from the ecosystem can be accomplished by advanced oxidation processes (AOP). AOPs are used preferably in treatment of wastewater. One of the AOP's methods is Fenton's reaction. The degradation of drug residues by this reaction was the aim the project. The experiments were focused on finding possible degradation products, which could be much more hazardous than parent compounds. The study was primarily concerned with non-steroidal anti-inflammatory drugs (acetaminophen, diclofenac, ibuprofen, naproxen and salicylic acid) and antiepileptic carbamazepine. The complete decomposition of tested compounds was not observed by using HPLC and MS analysis. The products of decomposition were found in reaction mixture, in case of diclofenac dechloration of aromatic ring occurred. In cases of most compounds with exception of acetoaminophen and salicylic acid the reaction led to the formation of more polar products than parent compounds. The results imply that even more advanced oxidation processes do not cause complete destruction of organic compounds. Key words: Fentons reaction, drug residues, acetaminophen, diclofenac, ibuprofen, carbamazepine, naproxen, salicylic acid.
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Analysis of solving processes of combinatorial problems at primary school (grade 1 - 3)
Tomešová, Lenka ; Slezáková, Jana (advisor) ; Jirotková, Darina (referee)
This diploma thesis deals with combinatorics in primary school teaching methods. The theoretical part is focused on characterisation of mathematical field of combinatorics, briefly describes it's historical evolution and basic types of combinatorial problems. This theoretical knowledge is further supplemented by an analysis of utilization rate of combinatorics in curiculative documents, selected textbooks and mathematical contests for primary school pupils. An essential part of the theoretical part of the work are chapters dealing with solving combinatorial problems. The practical part is based on research of solving combinatorial proceses on tasks for primary school pupils. KEYWORDS Combinatorics, combinatorial problem, typology of combinatorial problems, primary school pupil, solving peoceses, analysis of pupils'solving processes, number of solutions
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Hearing in the civil proceedings
Tomešová, Lenka ; Frintová, Dita (advisor) ; Kubešová, Silvia (referee)
1 Hearing in the civil proceedings - Abstract The diploma thesis deals with the course of hearing from its order, through the initiation to the end and issuance of the decision on the merits, since only properly run hearing is a guarantee of fair and complete hearing on the merits without delay. At the same time, the thesis pays attention to the principles that relate to hearing and whose observance ensures the participants right to a fair trial. The thesis will deal with the course of hearing both in adversarial and inquisitorial proceedings. The first chapter defines the concept of civil proceedings, hearing, and it is consequently stated by whom the proceedings are governed. The second chapter discusses the principles of hearing that are part of the right to a fair trial. It is a principle of public, oral and straightforward. When dealing with the principle of public, there is a certain amount of space devoted to the reasons for which the public can be absolutely or partially excluded from the hearing. The chapter also deals with the possibilities to ensure a dignified and undisturbed course of hearing, including ways and restrictions on the acquisition of audio and video recordings and transmissions from hearings. The longest and the most comprehensive chapter in the thesis is the third chapter, in...
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Analysis of cuticular extracts of bumblebees species Bombus terrestris
Tomešová, Lenka ; Valterová, Irena (advisor) ; Vrkoslav, Vladimír (referee)
Chemical substances are transferred between bumblebees of the species Bombus terrestris during their mating behavior. These substances are present mainly on the cuticle. The aim of this thesis was to identify and quantitatify differences in the amount of the compounds among defined groups of bumblebees - mated, non-mated and attempting to mate. Cuticular extracts were obtained by washing of the whole bumblebees bodies in hexane. These extracts were analyzed by using a two-dimensional gas chromatography with the time of fly mass spectrometr (GCxGC-TOF/MS). Cuticular hydrocarbons were identified and semi-quantified. Double bounds locations were determined in heptacosene and nonacosene. Five compounds were differed in the examined groups - β-springene, α-springene, dihydrofarnesyl-oleate, palmityl-palmitate and palmityl- palmitoleate. By comparing of the amount of these compounds differences between defined groups of bumblebees were determined. Analysis of the cutilar extracts showed that mated and non-mated bumblebees can be distinguished. Furthermore, there were statistically significant differences in the amounts of identified compounds in all defined groups of bumblebees. Key words: two-dimensional gas chromatography, Bombus terrestris, cutilar extract
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Use of Fenton Reaction for Drug Degradation in the Ecosystem
Tomešová, Lenka ; Smrček, Stanislav (advisor) ; Břichnáčová Habartová, Věra (referee)
The elimination of unwanted substances from the ecosystem can be accomplished by advanced oxidation processes (AOP). AOPs are used preferably in treatment of wastewater. One of the AOP's methods is Fenton's reaction. The degradation of drug residues by this reaction was the aim the project. The experiments were focused on finding possible degradation products, which could be much more hazardous than parent compounds. The study was primarily concerned with non-steroidal anti-inflammatory drugs (acetaminophen, diclofenac, ibuprofen, naproxen and salicylic acid) and antiepileptic carbamazepine. The complete decomposition of tested compounds was not observed by using HPLC and MS analysis. The products of decomposition were found in reaction mixture, in case of diclofenac dechloration of aromatic ring occurred. In cases of most compounds with exception of acetoaminophen and salicylic acid the reaction led to the formation of more polar products than parent compounds. The results imply that even more advanced oxidation processes do not cause complete destruction of organic compounds. Key words: Fentons reaction, drug residues, acetaminophen, diclofenac, ibuprofen, carbamazepine, naproxen, salicylic acid.
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