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Image registration
Jindra, Jakub ; Jiřík, Radovan (referee) ; Krátká, Lucie (advisor)
This bachelor thesis deals with various methods of image registration in the medical treatment. The criterias are elaborated for selecting the correct method of registration. This work describes parameters for proper transformation, identification, registration proces, a final assessment of registration for its approval and the corresponding evaluation. Some basic programs have already concerned with image registration and they are accompanied by basic information. This semester thesis also describes the basics of working with MRI and the creation of anatomical atlas from the magnetic resonation rat’s brain. In conclusion is described the creation of a simple graphical interface for viewing images of brain obtained from the magnetic resonance. Furthermore, the work deals with the registration of images according freely available programs and the related system of evaluation of these results. The scoring system is processed in a graphical users interface Matlab, where is used histograms, mosaic and evaluation using the cross.
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Optimization of the MRI chicken embryos measurements
Sedláčková, Gabriela ; Dražanová, Eva (referee) ; Krátká, Lucie (advisor)
This thesis deals with optimization of MRI measuring of phantoms containing the chicken embryo. The theoretical part of thesis is dedicated to the MRI fundamentals and description of pulse sequences. In the next part the options of keeping and monitoring the temperature are being discussed. The thesis also deals with design and realization of phantoms which are used for measuring. A browser of images captured by MRI was programmed in Matlab environment. The program allows users to look through the images with different settings of pulses sequences or kind of phantom. The final part of thesis describes the anatomical structures of chicken embryo and discussion of collected results.
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Arterial Spin Labeling MRI Data Analyzation
Galanová, Zuzana ; Jiřík, Radovan (referee) ; Krátká, Lucie (advisor)
This bachelor´s thesis is focusing mostly on perfusion imagining, which is done by the method of arterial spin labeling. It describes physical basics of nuclear magnetic resonance, image reconstruction, perfusion imagining without contrast substances, principles of arterial spin labeling and different ways of arterial spin labeling – mostly FAIR-RARE sequence, which belongs to the pulsed arterial spin labeling. One part of the thesis is dedicated to production of perfusion map in Matlab. Results are evaluated by comparison of data produced in Matlab and data produced in Paravision Version 5.1 and they are discussed.
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Image processing of MRI
Němcová, Simona ; Jiřík, Radovan (referee) ; Krátká, Lucie (advisor)
This thesis deals with the cartilage imaging using magnetic resonance. At first, there is mentioned physical principle of the magnetic resonance phenomenon and the most commonly used excitation sequences, followed by the description of the 9.4 T MR imaging system Bruker BioSpec 94/30 USR, which was used for measurement in the practical part. The next part is dedicated to the composition of cartilages and describes the temporomandibular joint, due to its suitability as an object for cartilage imaging. The series of MR scans of temporomandibular joint were taken with different acquisition parameters and evaluated by program designed through the MATLAB software. The program can be used for viewing scanned images, evaluating their contrast and determining the T1 relaxation time of the tissues by creating T1 maps.
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MRI Acquisition of Image Sequences for Preclinical Perfusion Imaging
Krátká, Lucie ; Bartoš, Michal (referee) ; Jiřík, Radovan (advisor)
The task of this thesis is to study methods for the acquisition perfusní imaging based on dynamic MR imaging with T1 contrast. It describes methods of measurement of T1 relaxation time and the possibility of evaluating the results. It further describes the phantoms and their use. And it is here mentioned for the dynamic acquisition protocol perfusní imaging. There is also described in detail created a program for automatic control of the NMR system. In the experimental measurements are performed on static and dynamic phantom, are also evaluated perfusion parameters from the Flash sequence.
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Fixation of the biological samples
Brachtl, Martin ; Jiřík, Radovan (referee) ; Krátká, Lucie (advisor)
The aim of thesis is acquaint with possibilities of fixation biological tissues. Choose a suitable tissue and fix it with formaldehyde and another fixator. Last but not least make measurements which determine effects of formaldehyde on the relaxation time of biological tissues. Mice brains were chosen as a suitable for tissues fixation. Measuring effects of formaldehyde and another fixator to relaxation time carried out at the Institute of Scientific Instuments Academy of Sciences of the Czech Republic.
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Flow Measurement - oriffice plates
Krátká, Lucie ; Málek, Petr (referee) ; Šedivá, Soňa (advisor)
The aim of the Bachelor thesis is to approximate the fluid flow measurement using differential pressure transducers inserted into fully filled circular cross-section conduits running full in the industrial sector. The introduction of the Bachelor thesis describes and explains the principle of fluid flow measurement using differential pressure transducers and the basic types of primary flow elements. Practical part consists of the design of practical calculations of individual parameters of standardized orifice plates, the design of a program for calculation of these parameters, comparing the achieved results with the output from the program Conval, evaluating these results and analyzing the measurement uncertainties for the parameters that affect the design of the standard orifice plate.
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Contrast MRI perfusion imaging
Šejnoha, Radim ; Harabiš, Vratislav (referee) ; Krátká, Lucie (advisor)
This semestral thesis is focused on contrast MRI perfusion imaging using method of Dynamic Contrast-Enhanced MRI. It describes basic principles of nuclear magnetic resonance and puls sequences used in DCE MRI. The thesis contains a part dedicated to dynamic contrast imaging of phantom with experimental NMR device located at the Institut of Scientific Instruments of the ASCR in Brno. Results of measurements are analyzed based on models and reached perfusion parameters are discussed.
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The effect of the MR pulse sequences on the measurement object temperature
Kosková, Markéta ; Jiřík, Radovan (referee) ; Krátká, Lucie (advisor)
This paper deals with the effect of the MR pulse sequences on the temperature of the measured object. The theoretical part is dedicated to basic principle of magnetic resonance, the selected pulse sequences and risks that are connected with MRI. There is also described the draft of the testing phantom and information about the measurement and record of temperature during MR measurement. In the experimental part the effect of RF coils, pulse sequences and parameters of pulse sequences are tested on drafted phantom with experimental MR device located at the Institut of Scientific Instruments of the AS CR in Brno. These findings are then tested on live laboratory mouse. All results are analyzed and used as default data for developed simulation program.
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Non-contrast MRI perfusion imaging
Kruml, Ondřej ; Jiřík, Radovan (referee) ; Krátká, Lucie (advisor)
This bachelor paper is focused on the magnetic resonance perfusion imaging technic without the usage of an external contrast media. This paper contains a look at the basic functional principle of the magnetic resonance. The focus is then set set on the Arterial Spin Labeling (ASL) technic. The basic principle of ASL uses protons from the water mocelules in arterial blood as an endogenous contrast agent. This technic can be used for obtaining a perfusion map of any tissue without the usage of invasiont echnics or contrast agents. The quantification of perusion was done applying the FAIR-RARE scheme, which belongs to the large family pulsed ASL.
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