National Repository of Grey Literature 66 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
The role of adrenergic system in genetic hypertension
Loučková, Anna ; Kadlecová, Michaela (advisor) ; Husková, Zuzana (referee)
The adrenergic system plays an important role in the regulation of blood pressure. In the spontaneously hypertensive rat, the most studied model of essential hypertension, many components of the adrenergic system are altered. Changes in expression level of any catecholamine biosynthetic enzymes or any adrenergic receptor subtypes could be one of the causes of hypertension development. In this work, the expression of adrenergic system genes was measured in adrenal gland, renal cortex and renal medulla of the spontaneously hypertensive (SHR), Wistar-Kyoto and Brown Norway rats at the age of thirteen weeks. In adrenal gland of SHR, all four catecholamine biosynthetic enzymes (tyrosine hydroxylase, DOPA decarboxylase, dopamine β-hydroxylase and phenylethanolamine-N- methyltransferase) and almost all subtypes of adrenergic receptors (with the exception of Adra1a and Adra1d) were underexpressed. This generally decreased expression in adrenal gland of SHR suggests that at least a part of regulation of adrenergic system gene expression is common. The mechanism of this downregulation in SHR could be a negative feedback through adrenergic receptors stimulated by high plasma noradrenaline concentration. In the kidney of SHR, there were no differences in the expression of most of adrenergic receptor subtypes with the...
The reflective effect of manipulative therapy on blood pressure.
Martínek, Josef ; Bitnar, Petr (advisor) ; Slabý, Kryštof (referee)
The topic of the thesis is The reflective effect of manipulative therapy on blood pressure. The aim of the thesis is to summarize current knowledge, which talk about the relationship between the ma-nipulative therapy and the changes of blood pressure. One of the purpose of the thesis is to clarify the using of manipulative therapy in the treatment of arterial hypertension. In the thesis another methods of manipulative therapy are discussed to give broad overwiev and to have a posibble to comparison. Powered by TCPDF (
Systemic arterial hypertension and strain
Sakaláš, Radovan ; Radvanský, Jiří (advisor) ; Procházka, Miroslav (referee)
Bachelor thesis "Systemic arterial hypertension and exercise" deals with hypertension and exercise. Physiology of the circulatory system, as well as blood pressure regulation and measurement is covered in the first section. The next section discusses definition, classification, and subtype classification. Furthermore, the thesis discusses pharmacological and non-pharmacological treatment of hypertension. The main part of the thesis covers exercise blood pressure reaction as a diagnostic tool for determining risk for future hypertension. Moreover, exercise and physical activity is described as a therapeutic tool in blood pressure reduction. This section compares and determines the intensity, frequency, and period of endurance and resistance training needed for an optimal blood pressure reduction. The final section is dedicated to the mechanisms of exercise effect on blood pressure. Powered by TCPDF (
Influence of defined olfactory stimuli to selected physiological parameters
Mažárová, Silvia ; Pánek, David (advisor) ; Vláčilová, Ivana (referee)
Title: Influence of defined olfactory stimuli to selected physiological parameters Objectives: Comparing the effect of inhibiting and stimulating scents on the chosen physiological parameters during a 20 minute long inhalation. The thesis is searching for the possible affections to cardiovascular system and to reactibility of the neuromuscular system of the aromatherapy. Methods: 10 individuals participated on the trial, 5 females and 5 male. As the inhibiting scent we chose essential oil of Lavandula angustifolia and as the stimulating scent Rosmarinus officinalis. The observed physiological parameters was heart rate, blood pressure, present emotional state using the Visual Analogue Mood Scale by Stern, results of the Petries' test and standing on two scales test. The chosen application form of the essential oils was inhalation. The observed parameters were recorded before the application of scents, in the 10th and 20th minute of the application and 20 minutes after the end of application. We used the method of comparison. With statistical analysis we compared the results of the mentioned tests and diagnostic methods before and after application each of the odors. Results: We consider that Lavandula angustifolia and Rosmarinus officinalis have statistically significant effect to cardiovascular...
The effect of sauna on the changes of blood pressure
Benko, Michal ; Bunc, Václav (advisor) ; Heller, Jan (referee)
Title: The effect of sauna on the changes of blood pressure Objectives: The aim of this study was the measure of the physiological range (blood pressure, heart rate, blood oxygen saturation) of two selected groups of people within the sauna cycle, assess changes and compare the results of individual probands and groups. Methods: This thesis is conducted as an experimental study. This is a quantitative method, in that will be at first established hypotheses and then evaluated on the basis of the obtained results. The independent variable in this research is the sauna and dependent variables are blood pressure, heart rate and blood oxygen saturation. Results: Blood pressure values were at employee of sauna lower than at other probands, thereby was confirmed hypothesis, but expected significant differences between the measured values of each group were absent. At the same time there was a further confirmation of the hypothesis concerning heart rate, which was increased at all probands. The last confirmed hypothesis related to the blood oxygen saturation and its reduce after the sauna. It could be said that all the defined hypotheses were confirmed. Keywords: sauna, blood pressure, heart rate, blood oxygen saturation, cardiovascular system
The Possible Assessments of Unprofessional Exposures of Low Frequency Noise
Potužníková, Dana ; Fiala, Zdeněk (advisor) ; Bencko, Vladimír (referee) ; Argalášová, Ĺubica (referee)
v anglickém jazyce The possible assessments of unprofessional exposures of low frequency noise Introduction: Along with technical development, the number of sources of low frequency noise increases in the human environment and the number of complaints from people exposed to noise from these sources increases as well. The statutory limit for non-professional exposure to low frequency noise has not yet been established (due to the limited amount of data on low frequency noise exposure risks) in the EU countries (USA) and no WHO recommendations have been issued in this area. For these reasons, the hygienic limit for municipal/non-professional exposure to low frequency noise was not specified in the Czech Republic. Objecticve: The present dissertation thesis was to investigate whether the short-term experimental exposure to low frequency noise with the tonic component induces significant changes in the circadian rhythm of cortisol and alpha-amylase in saliva in the experimental set of volunteers. Saliva is a biological material that allows low-invasiveness collection. The work was supposed to assess whether possible changes could be used as objective indicators of the presence of the stress response to the noise exposure. Material and metods: An experimental study was conducted on a set of 100...
The impact of ambient temperature on exertion parametres and their dynamics
Bělohlávek, Jiří ; Procházka, Michal (advisor) ; Slabý, Kryštof (referee)
The aim of the work was comparing physiological mechanisms of mainly cardiopulmonary and respiratory system given different temperatures. The outcome will be review article bringing together studies, which are commonly focused just on one temperature extreme, therefore offering complex overview of the issue. The review article will be completed with realization of own experiment. Powered by TCPDF (
Evaluation of results using different methods of experimental measuring of blood pressure amongst students of the First Faculty of Medicine of the Charles University
Sova, Jan ; Kymplová, Jaroslava (advisor) ; Jirsa, Jan (referee)
During the projects from biophysics of freshman students of the Faculty of Medicine the pressure measurement is run by several different methods; palpation, auscultatory and digital method. Students are learning to record the measurement in a systematic way, and they are learning to compare the results of every method to each other. The measurement of systolic and diastolic pressure are dependent on each other of course, as well they are dependent on the set of biometric and other information that is well available in healthy students (sex, height, weight, physical strain etc.). The aim of the thesis is to compare the results acquired by the methods of measurement mentioned above, related to the accuracy of the scattering of the measurement and related to the anticipated standard values of healthy individuals. The basis of the thesis is going to be project and creation of the regression model for the levels of systolic/diastolic pressure measured out that is dependent on biometric data along with the testing of statistical importance of parametres through the procedure of multifactorial ANOVA for the repeated measurement. The result will aim to show both advantages and disadvantages of different methods of the pressure measurement during accordingly varying conditions of experiments. The thesis...
Possibilities of influencing blood pressure in spinal cord injury patients during verticalization
Věchetová, Tereza ; Schreier, Bronislav (advisor) ; Slabý, Kryštof (referee)
Orthostatic hypotension is a common problem for individuals with spinal cord lesions, especially in the acute period after spinal cord injury. The first part of this study deals with the theoretical analysis of the pathophysiology of cardiovascular control after spinal cord injury, the definition of orthostatic hypotension and its inclusion within the classification of the syncopal conditions. An important part of the theoretical part is the management of orthostatic hypotension, which brings non-pharmacological therapeutic approaches, and marginally pharmacology, to decrease the severity of this condition. The experimental part focuses on testing of a group of probands with spinal cord injury (11 quadriplegics) on two different types of tilt tables according to the same protocol. The first tilt table is a standard; the second one is Erigo, tilt table with integrated robotic mechanism, which moves the legs to simulate walking. The parameters, such as blood pressure, heart rate, oxygen saturation, and the occurrence and severity of pre-synkopal symptoms, were compared. The study is based on the assumption that passive leg movement, which is mediated by the Erigo, will maintain venous return, cardiac output, and a significant drop in blood pressure and development of orthostatic hypotension,...
Effect of regularly applied nordic walking on selected cardiorespiratory parameters in adults after heart valve surgery
Tejnecká, Michaela ; Daďová, Klára (advisor) ; Malá, Michaela (referee)
Author: Bc. Michaela Tejnecká Title: The effect of regularly applied Nordic walking on selected cardiorespiratory parameters in adults after heart valve surgery. Aim: The aim of this work was to analyze the effect of six months of Nordic walking intervention on selected casrdiorespiratory parameters in adults after heart valve surgery. Methods: The study included ten individuals (mean age 62 years) who were at least five years apart after heart valve surgery. Blood pressure (BP) was measured using a pulsed wrist tonometer, blood oxygen saturation (BOS) and heart rate (HR) were measured using a pulse oximeter, and the ejection fraction of the heart (EF) was evaluated echocardiographically. Nordic walking training units took plaxe once a week for 6 months. During this intervention, the level of training gradually increased both in distance and elevation of the terrain. Results: In all probands there was an average reduction in systolic blood pressure during exercise by an average of 10,3 mmHg and a reductionin heart rate during exercise by an average of 24 beats per minute. The resting ejection fraction increased by an average of 5,5% after six month intervention. These changes were statistically significant (p<0,01). The results of the work point to the benefits of Nordic walking for cardiac...

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