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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
The pathogenesis of autism in relation to maternal antibodies: from molecule to connectome
 Rusková, Lívia ; Jiruška, Přemysl (advisor) ; Míková, Hana (referee)
Autism is a neurological disease that affects predominantly boys. It is characterised by anti- social and stereotypical behaviour with a low level of empathy. Most of the studies have been focusing on the genetic aetiology of this disease, however in the past years research has focused on the role of maternal immune system. This thesis is putting together information predominantly about maternal autoimmune antibodies that recognize specific proteins important in neurogenesis. It is focusing on the function of these proteins in neurogenesis and their possible correlation with the pathological brain connectome in autism. Key words: autism, maternal antibodies, connectome, neurodevelopment
Detailed record
The pathogenesis of autism in relation to maternal antibodies: from molecule to connectome
 Rusková, Lívia ; Jiruška, Přemysl (advisor) ; Míková, Hana (referee)
Autism is a neurological disease that affects predominantly boys. It is characterised by anti- social and stereotypical behaviour with a low level of empathy. Most of the studies have been focusing on the genetic aetiology of this disease, however in the past years research has focused on the role of maternal immune system. This thesis is putting together information predominantly about maternal autoimmune antibodies that recognize specific proteins important in neurogenesis. It is focusing on the function of these proteins in neurogenesis and their possible correlation with the pathological brain connectome in autism. Key words: autism, maternal antibodies, connectome, neurodevelopment
Detailed record

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