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National Repository of Grey Literature

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Morphological changes in pulmonary vascular bed after pulmonary embolism Vavera, Zdeněk ; Vojáček, Jan (advisor) ; Staněk, Vladimír (referee) ; Vítovec, Jiří (referee) Introduction: Chronic thromboembolic pulmonary hypertension (CTEPH) is a relatively common long-term complication of acute pulmonary embolism (PE) with severely negative impact on the patient's quality of life and prognosis. Specific pharmacotherapy and especially mastery of pulmonary endarterectomy (PEA) offer to our patients a hope for eventual full recovery. Early diagnosis determination is crucial. Objective: The aim of our prospective study was to determinate CTEPH incidence in a population of patients after acute pulmonary embolism as the first venous thromboembolic event in the patient`s history, to assess morphological changes in the pulmonary vascular bed with regard to risk of CTEPH development and try to identify some risk factors of CTEPH development. Methods: 120 consecutive patients with acute PE were followed-up for 2 years. On admission patients underwent CT pulmonary angiography (CTA), echocardiography and troponin-T, NT-proBNP and D-dimer assessement. At the time of hospital discharge we performed echocardiography and biomarkers reassessement whether they were elevated initially. After 6 months patients underwent pulmonary CTA, echocardiography and during 12- and 24-months visits echocardiography was performed again. In case of pulmonary hypertension detection CTEPH was confirmed... Detailed record

Morfologické změny plicního řečiště po plicní embolii Vavera, Zdeněk ; Vojáček, Jan ; Fakultní nemocnice (Hradec Králové, Česko) Detailed record

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