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An overview of instruments usable for evaluation of instrumental activities of daily living in
Tipková, Zuzana ; Rodová, Zuzana (advisor) ; Rejtarová, Anna (referee)
The bachelor thesis is theoretical and deals with the topic of evaluation of instrumental activities of daily living (IADL). The theoretical part describes what are instrumental activities of daily living and their importance in terms of independent living and participation of an individual in society. It includes a chapter of evaluation in occupational therapy, which states reasons, approaches, principles and types of evaluation, important characteristics of assessment tools, the way how to select the tool and what impact does the loss of ability to perform ADL have on an individual's social participation. The aim of the bachelor thesis is to analyse the literature and to create an overview of standardized assessment tools for the evaluation of instrumental ADL, which can be used in adults with various types of diagnoses. At the end of the thesis is a table of selected tools, which shows some characteristics such as short description, approximate time of administration, price, target group of patients and language. Kettle test was translated with permission of the authors and can be found in the Appendices.
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CEA in breeds used for dog-assisted activities and therapies
Tipková, Zuzana ; Sedláková, Vladimíra (advisor) ; Fiala Šebková, Naděžda (referee)
Collie Eye Anomaly (CEA) is an inherited disease that primarily affects herding dog breeds such as Smooth and Rough Collie, Border Collie, Shetland Sheepdog and Australian Shepherd, as well as Nova Scotia Duck Tolling Retriever. All these breeds can be used for dog-assisted activities, some individuals are also suitable for dog-assisted therapies. In the literature I found general information about the history, symptoms, diagnosis, mode of inheritance, genetic testing of the predisposed breeds.
CEA was first described in the 50s of the 20th century. Manifestations of CEA vary widely and therefore it has not been known that a variety of symptoms is caused by one disease for a long time.
Choroidal hypoplasia is the characteristic sign, furthermore may be present: coloboma, tortuosity of the retinal blood vessels, intraocular hemorrhage and retinal detachment leading to blindness. CEA cannot be cured. It is recommended to perform an early diagnosis, which is possible from 6 to 8 weeks of age, because the defect can be covered by later pigmentation in older pups and ocular fundus of the dog then appears normal. At first dog breeders did not pay much attention to this anomaly, because it is a small percentage of individuals who become completely blind as a consequence of that disease. Carriers of CEA have no symptoms, but their offspring may inherit a severe form of CEA. We cannot exclude affected individuals from breeding program in the breeds with high prevalence of CEA since it would reduce genetic diversity.
It is an autosomal recessive disease caused by mutation in the NHEJ1 gene. After the causative mutation was found, a two-step PCR assay, which uses two primer pairs to quickly detect the mutation in chromosomes, was developed. The latest molecular methods for the diagnosis of CEA include simplified analysis of the deletion without DNA isolation and rapid genotyping technique based on SYBR Green real-time PCR. Genetic tests are available in many countries now and so breeders can control the health of their dogs.
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