|
|
Influence of Botulinum Toxin Application on Quality of Life in Patients with Multiple Sclerosis
Miňová, Zuzana ; Jirásková, Lucie (advisor) ; Kövári, Martina (referee)
The aim of the bachelor's thesis is to find out how medical application of botulinum toxin can affect the quality of life in patients with multiple sclerosis. The thesis is based on theoretical research providing a brief overview of the basic facts about multiple sclerosis - its pathogenesis, etiology, clinical picture, treatment alternatives. Further on, the thesis deals with the concept of spasticity, possibilities to influence it and also its valuation. The subsequent section comprises an overview of the findings about botulinum toxin and its therapeutic application. The term quality of life, an influence of the disease on the quality of life and also the methods used to evaluate it are described at the end of the theoretical part. The practical section contains case histories of two patients who underwent the medical application of botulinum toxin. The thesis is closed by a discussion on this topic. Powered by TCPDF (www.tcpdf.org)
|
|
|
The effect of prolonged stretching on spastic muscle contracture before and after Botulinum toxin A application
Miňová, Zuzana ; Hojková, Klára (advisor) ; Kövári, Martina (referee)
A large proportion of patients with central motoneuron lesions is at risk of spastic paresis and formation of contractures. One of the therapeutic techniques used in patients with spastic paresis is prolonged stretching. The theoretical part summarizes the knowledge regarding spastic paresis, its clinical evaluation, the development of contractures and therapeutic interventions, especially botulinum toxin (BTX) and stretching. The aim of this study was to compare the effectiveness of prolonged stretching on spastic muscle contracture before and after BTX application. In our retrospective comparative study there were included 30 patients divided into two groups. The first group consisted of 15 patients performing prolonged stretching of the m. rectus femoris (m. RF) for three months according to Guided Self-rehabilitation Contract of Professor J. M. Gracies. The second group (15 patients) performing the same procedure, but at the same time BTX was injected into the m. RF. We monitored the change in passive knee joint range of motion into flexion and the change in 10MWT time. Statistical evaluation showed that the difference in knee joint range of motion after three months of performing prolonged stretching was statistically insignificant (p=0.194). The difference in knee joint range of motion after...
|
|
|
Influence of Botulinum Toxin Application on Quality of Life in Patients with Multiple Sclerosis
Miňová, Zuzana ; Jirásková, Lucie (advisor) ; Kövári, Martina (referee)
The aim of the bachelor's thesis is to find out how medical application of botulinum toxin can affect the quality of life in patients with multiple sclerosis. The thesis is based on theoretical research providing a brief overview of the basic facts about multiple sclerosis - its pathogenesis, etiology, clinical picture, treatment alternatives. Further on, the thesis deals with the concept of spasticity, possibilities to influence it and also its valuation. The subsequent section comprises an overview of the findings about botulinum toxin and its therapeutic application. The term quality of life, an influence of the disease on the quality of life and also the methods used to evaluate it are described at the end of the theoretical part. The practical section contains case histories of two patients who underwent the medical application of botulinum toxin. The thesis is closed by a discussion on this topic. Powered by TCPDF (www.tcpdf.org)
|
guest ::
