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Monitoring of brain activity in critical sick newborns
Zemánková, Jana ; Kokštein, Zdeněk (advisor) ; Kantor, Lumír (referee) ; Dort, Jiří (referee)
Monitoring of brain activity in critical sick newbornss The aim of the study was evaluation of brain aktivity in neonates with perinatal asphyxia and correlation with short-term and long-term outcome. The second part of this work is focused on maturation of brain activity in preterm newborns. We assessed traces in 88 neonates suffered from perinatal asphyxia (pH 6,96, BE -16,9) in the first part. aEEG traces were evaluated according classification by Hellström-Westas, short-term outcome was evaluated as development of hypoxic-ischemic encephalopathy (classification Sarnat-Sarnat). We divided children into 4 groups for assessment of long-term outcome - normal outcome, mild psychomotoric delay, severe psychomotoric retardation, death in perinatal period. We evaluated relation between aEEG, short-term and long- term outcome and biochemical markers of hypoxia (pH, BE, lactate) and Apgar score. We reached SE 77 %, SP 100 %, PPV 100 %, NPV 74 % in assessment of correlation between aEEG and short-term outcome, SE 92 %, SP 81 %, PPV 74 % a NPV 94 % in relation between aEEG and long-term outcome and SE 100 %, SP 66 %., PPV 64 %., NPV 100 % in correlation between HIE and long-term outcome. There was gained statistically significant dependence between aEEG and umbilical pH, between lactate and aEEG, short-term...
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Monitoring of brain activity in critical sick newborns
Zemánková, Jana ; Kokštein, Zdeněk (advisor) ; Kantor, Lumír (referee) ; Dort, Jiří (referee)
Monitoring of brain activity in critical sick newbornss The aim of the study was evaluation of brain aktivity in neonates with perinatal asphyxia and correlation with short-term and long-term outcome. The second part of this work is focused on maturation of brain activity in preterm newborns. We assessed traces in 88 neonates suffered from perinatal asphyxia (pH 6,96, BE -16,9) in the first part. aEEG traces were evaluated according classification by Hellström-Westas, short-term outcome was evaluated as development of hypoxic-ischemic encephalopathy (classification Sarnat-Sarnat). We divided children into 4 groups for assessment of long-term outcome - normal outcome, mild psychomotoric delay, severe psychomotoric retardation, death in perinatal period. We evaluated relation between aEEG, short-term and long- term outcome and biochemical markers of hypoxia (pH, BE, lactate) and Apgar score. We reached SE 77 %, SP 100 %, PPV 100 %, NPV 74 % in assessment of correlation between aEEG and short-term outcome, SE 92 %, SP 81 %, PPV 74 % a NPV 94 % in relation between aEEG and long-term outcome and SE 100 %, SP 66 %., PPV 64 %., NPV 100 % in correlation between HIE and long-term outcome. There was gained statistically significant dependence between aEEG and umbilical pH, between lactate and aEEG, short-term...
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