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National Repository of Grey Literature

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The applications of the Human Biomonitoring Method for estimation of exposure and load of the Czech Population and International Comparison Forysová, Kateřina ; Černá, Milena (advisor) ; Fiala, Zdeněk (referee) ; Mráz, Jaroslav (referee) Human biomonitoring (HBM) is an important tool for monitoring human exposure to chemical pollutants from the environment and their possible adverse effects on the health of the population. HBM is defined as the monitoring and quantification of environmental chemicals, their metabolites or other changes related to exposure in human body fluids and tissues. The monitored biomarkers in this work are cadmium, mercury, cotinine and metabolites of phthalates. While mercury and cadmium are long-term biomarkers in the Czech Republic, cotinine and phthalate metabolites were determined for the first time. The presented work was a part of the pilot international study DEMOCOPHES, which focused on determining the exposure of increasingly susceptible population groups to the mentioned chemical noxas. In this work, the exposure of Czech children and their mothers living in urban and rural environments and the influence of environmental factors, lifestyle and social status on this burden were monitored. Another aim of the work was to compare the results of mercury and cadmium concentrations from the DEMOCOPHES project with the results obtained within the Health Monitoring System in relation to the population of the population in the Liberec Region in the years 1996 - 2016. The results showed that the levels of Cd... Detailed record

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