Home > Search Results: Cibulková, Ivana
Search:
Search Tips :: Advanced Search
Search collections:
Sort by: Display results: Output format:
National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Effect of antibiotic administration in the early stages of ICU stay on the microbiome of the oral cavity and upper respiratory tract
 Gusarova, Bogdana ; Duška, František (advisor) ; Cibulková, Ivana (referee)
Objectives: The primary goals of this study are to describe the dynamics of the oral microbiome and the microbiome of the upper respiratory tract in patients subjected to mechanical ventilation, and to provide a detailed description of quantitative and qualitative changes in the composition of the oral microbiome following the administration of antibiotic therapy. Methodology: The research was designed as a prospective observational case-control study. From March to June 2023, twenty patients were included in this study. They were hospitalized at the Anesthesiology and Resuscitation Clinic of Královské Vinohrady University Hospital and met the established criteria. Samples from the gingival area and the root of the tongue were collected from each patient before and after antibiotic administration. The samples were subsequently processed using the 16S ribosomal RNA gene sequencing method. Results: The primary finding of the research project was the dynamics of the microbiome. Our study revealed that intubation leads to a shift of the microbial community from the oral cavity to the root of the tongue within a matter of days, or for some patients, even within hours. Furthermore, the administration of antibiotic therapy had a significant negative impact on the growth of bacterial flora in the oral...
Detailed record

See also: similar author names
2 Cibulková, Iva
Interested in being notified about new results for this query?
Subscribe to the RSS feed.
Digital Repository :: Search :: Submit :: Personalize :: Help
Powered by Invenio v1.1.2
Maintained by admin.invenio@techlib.cz
This site is also available in the following languages:
Česky  English