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Evaluation of the Financial Situation in the Firm and Proposals to its Improvement
Cejpková, Monika ; Žižlavský, Ondřej (referee) ; Bartoš, Vojtěch (advisor)
The aim of this thesis is evaluation of the financial situation of the company Pivovary Staropramen a.s. between 2007 and 2009. This was completed using methods of financial analysis, and possible improvements were suggested based on the research outcome. At first, this paper focuses on introduction of the organization. Following, the theoretical section explains given terminology, methods and measurements. The practical part consists of calculations and financial analysis including the interpretation of the research results. At last, the financial situation within the given time frame is explained and summarised, and suggestions for improvement are provided.
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Comparison of selected methods of valuation of a holiday cottage in the location of Hanušovice
Cejpková, Monika ; Bradáč, Albert (referee) ; Štola, Josef (advisor)
This diploma thesis, in its theoretical part, focuses on the basic concepts of the real estate valuations and the description of valuation methods followed by description of the selected locations. The practical part contains description of five specific objects of type Holliday Cottage in Hanušovice and then applies the valuation methods. In this work are used these valuation methods: - Awarding the comparative way according to valid Regulations - The expenditure method of valuation - Direct comparison method As a result will be an assessment of properties of the used methods and an evaluation of the most appropriate method for the type of property Holiday Cottage in this area.
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The role of cholesterol 7alpha-hydroxylase in regulation of cholesterolemia
Cejpková, Monika ; Kovář, Jan (advisor) ; Leníček, Martin (referee)
The aim of the theses is to characterize the mechanism that participate in the regulation of activity of cholesterol 7α-hydroxylase (CYP7A1) - the key enzyme of classical pathway of bile acids synthesis. The function and metabolism of cholesterol and bile acid is described at the beginning. Cholesterol is a substrate for CYP7A1 and bile acids are produced in the reaction catalyzed by the enzyme. The other parth of theses is dedicated to feedback inhibition of CYP7A1 by bile acids and describes particular regulatory pathways involved. The crucial factors for CYP7A1 expression are bile acids response elements (BARE) in the promoter of CYP7A1 gene. Central role is played by farnesoid X receptor activated by bile salts that induces expression of protein called small heterodimer partner (SHP) in the liver. SHP interacts with trancription factors in BARE and inhibits CYP7A1 transcription. In the instestine FXR induces fibroblast growth factor 19 (FGF19) that activates signalling pathways leading to inhibition of CYP7A1 in the liver. The activity of CYP7A1 can be regulated independently of FXR - there is a role for hormones (insulin, glucagon), glucose, activation of proinflammatory cytokines and other nuclear receptors (pregnane X receptor and vitamin D receptor), that participate in protection of the...
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Evaluation of the Financial Situation in the Firm and Proposals to its Improvement
Cejpková, Monika ; Žižlavský, Ondřej (referee) ; Bartoš, Vojtěch (advisor)
The aim of this thesis is evaluation of the financial situation of the company Pivovary Staropramen a.s. between 2007 and 2009. This was completed using methods of financial analysis, and possible improvements were suggested based on the research outcome. At first, this paper focuses on introduction of the organization. Following, the theoretical section explains given terminology, methods and measurements. The practical part consists of calculations and financial analysis including the interpretation of the research results. At last, the financial situation within the given time frame is explained and summarised, and suggestions for improvement are provided.
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Comparison of selected methods of valuation of a holiday cottage in the location of Hanušovice
Cejpková, Monika ; Bradáč, Albert (referee) ; Štola, Josef (advisor)
This diploma thesis, in its theoretical part, focuses on the basic concepts of the real estate valuations and the description of valuation methods followed by description of the selected locations. The practical part contains description of five specific objects of type Holliday Cottage in Hanušovice and then applies the valuation methods. In this work are used these valuation methods: - Awarding the comparative way according to valid Regulations - The expenditure method of valuation - Direct comparison method As a result will be an assessment of properties of the used methods and an evaluation of the most appropriate method for the type of property Holiday Cottage in this area.
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