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National Repository of Grey Literature

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	Spatial Sructure of Chromosome 17 Territory in the Interphase Nucleus of Human Lymphocytes Lukášová, Emilie ; Kozubek, Stanislav ; Kozubek, Michal ; Falk, Martin ; Amrichová, J. ; Jirsová, Pavla ; Bártová, Eva A study on the spatial structure of chromosome 17 territory in the interphase nucleus of human lymphocytes Detailed record
	Spatial Distribution of Subtelomeric DNA Sequences in Human G0 and Stimulated T-lymphocytes Amrichová, J. ; Lukášová, Emilie ; Kozubek, Stanislav ; Jirsová, Pavla ; Kozubek, Michal A description of the spatial distribution of subtelomeric DNA sequences in human lymphocytes Detailed record
	Využití vysokorozlišovací cytometrie ke studiu živých buněk Vařecha, M. ; Amrichová, J. ; Ondřej, Vladan ; Lukášová, Emilie ; Kozubek, Stanislav ; Matula, Pa. ; Matula, Pe. ; Kozubek, Michal The fluorescent proteins are important innovation in the field of cell biology and in vivo experiments that use fluorescent proteins bring new interesting results from a different point of view than in vitro and in situ experiments. This presentation will introduce our automated 2D/3D high-resolution time-lapse image acquisition and analysis of living cells transfected with plasmids encoding fusion proteins or dyed with fluorescence probes. One of our in vivo projects, we will mention, is focused on the study of mitochondrial and nuclear apoptotic processes in living cells. Another in vivo project concentrates on the study of topography of telomeres and incidence of telomere-association phenomenon in various types of human tumor and healthy cells. In our experiments, cells are stably or transiently transfected with plasmid DNAs coding mitochondrial apoptogenic or telomere-binding proteins with fluorescent proteins. Detailed record

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