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Experimental models of increased physical activity for cardiovascular research
Ševčíková, Anežka ; Kolář, František (advisor) ; Kašík, Petr (referee)
This thesis provides a critical review of experimental models and protocols of increased physical activity that have been used for various purposes in cardiovascular research in small laboratory rodents. The thesis describes their physiological and pathophysiological effects and evaluates the advantages and disadvantages of using each model to study the adaptive mechanisms and beneficial effects of physical activity on cardiovascular disease. The use of physical activity in cardiovascular patients or people with cardiovascular risk factors is also mentioned. A review of exercise stress tests used to detect the degree of experimental heart failure of various etiologies and specific examples are also included. Key words physical activity, endurance training, stress test, small laboratory animals, heart, hypertrophy, therapeutic effects

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