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Epigenetika u zvířat
Abramov, Dmytro
Epigenetics studies changes in the function of genes that do not affect the primary nucleotide sequence of the DNA strand. In recent years, significant progress has been made in the study of epigenetic mechanisms, and it has been shown that epigenetic modifications have an enhanced effect not only during growth and development, but also during the phase of active ageing. The functions of DNA methylation have been determined, histone modifications and changes in chromatin structure have been described in more detail, and the role of RNA regulation of gene expression in various organisms has been clarified. The main aim of this bachelor thesis was to summarize the fundamental knowledge of epigenetic processes in animal organisms with a focus on mammalian laboratory models. Also in this literature review the focus was specifically on epigenetic changes in mammalian gamete and embryo development, epigenetics of animal health and epigenetic mechanisms of aging. In addition, processes that influence the animal breeding process were also described.

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