National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Antivirotické účinky biologicky aktivních látek z přírodních zdrojů v kombinaci s imunomodulačními látkami proti viru klíšťové encefalitidy
ČERNÝ, Jan
The aim of this study is focused on substances from the nature as a potentional treatment against tick-born encephalitis virus. The research of this master thesis can be divided into two sections. The first one is about choosen derivatives of adamantane, their cytotoxic effect on neuron cell lines and the determination of their antivirotic properties in vitro. For these purposes was used the combination of MTT assay, plaque titration assay and one-step qRT-PCR. The second part of this work verified the capability of choosen stilbenes to prolong the life of BALB/c mice which were infected by tick-born encephalitis virus.

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