National Repository of Grey Literature 1 records found  Search took 0.01 seconds. 
Framework for retrieval and analysis of proteins apo and holo forms from PDB
Král, Adam ; Hoksza, David (advisor) ; Novotný, Marian (referee)
We developed a software framework that allows the analysis of ligand-free (apo) and ligand-bound (holo) forms of proteins that are accessible in PDB. The software downloads the current version of the PDB, divides the structures into groups of the same molecules, and these into apo and holo forms. Finally, it is possible to analyze pairs of apo and holo structures with respect to their different structural characteristics. In addition to the software work itself, we present the results of selected analyses of the current version of the data in the PDB. We also verify the results against previous work.

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