National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Fenotypová charakteristika monocytov a makrofagov prasiat vykrmovaných rôznymi dietámi
Bátik, Andrej
Many research articles describes fish oil as a beneficial for health. Mainly for prevention of cardiovascular diseases or that fish oil reduces cholesterol in blood stream. Aim of this study is to investigate effects of fish oil specifically of his parts EPA+DHA, on a modulation of immune system and phenotypic differentiation. For the experiment were chosen monocytes and macrophages obtained from experimental group of animals which was fed a diet consist of the addition of fish oil in an amount 45mg/kg of live weight. Then inflammatory state was induced by LPS. Cells surface receptors were analyze through flow cytometry specifically CD14, CD163, SLA-DR and theirs combinations after they were statistically processed. Results shows proinflammatory effects of fish oil however they were statistically not significant.
The importance of vitamin D and calcium in the human diet
Bártová, Magdaléna ; Hejtmánková, Alena (advisor) ; Michlová, Tereza (referee)
Vitamin D refers to a group of fat soluble steroids. The most important forms are cholecalciferol occurring in foods of the animal origin and ergocalciferol of the plant origin. Human accept them in the diet; the fatty fishes, fish liver, and some other foods like milk, eggs or yeasts are rich resources of vitamin D. Unlike the other vitamins, the synthesis of vitamin D can also take place in the living body. Cholecalciferol is formed in the skin from its precursor 7 - dehydrocholesterol by the effect of UVB radiation. The conversion efficiency depends on various factors. Two successive reaction steps are necessary for the activation of vitamin D. The first step of hydroxylation occurs in the liver to be formed calcidiol. Calcidiol is the principal form of vitamin D in the blood acting also as the indicator of body supplies. The second one takes place in the kidneys where calcidiol is transformed to calcitriol. Calcitriol is assumed as the active hormonal form of vitamin D binding to the receptor for vitamin D - VDR. The best known and the most explored function is the effect of vitamin D on the calcium and phosphorus homeostasis. Consequently, vitamin D also influences the proper functions of muscles and the immune system. It reduces the risk of the cancer and cardiovascular diseases by various mechanisms as well. However, there are assumed another effects of vitamin D on the human body, which are not fully yet understood and are the subject for further research. Calcium constitutes the major mineral component of bones and teeth. It is an essential nutrient and therefore it is necessary to supply it with food. Its content in foods is various as well as its usability from these. The major resources of calcium are milk and dairy products. Calcium is also present in eggs, mineral waters, certain fishes and food of plant origin. Especially, the plant resources usability of calcium is limited because of the insolubility of some calcium complexes. Calcium is essential for the composition structure of bones and teeth. Besides of structural function, it has a main role in the blood coagulation, neuromuscular transmission or muscle contraction. Vitamin D has an influence on the usability of calcium because of the efficiency increase of calcium absorption in the intestine. The lack of both micronutrients leads to skeletal diseases - osteoporosis, osteomalacia and rickets. The adequate intake of both essential part of food, vitamin D and calcium, is important especially for the growing children, elderly people, and pregnant and lactating women.

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