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Literature search of possibilities of computational modelling of brain aneurysms
Lipenský, Zdeněk ; Polzer, Stanislav (referee) ; Burša, Jiří (advisor)
This bachelor thesis is focused on gathering general information about a cerebrovascular disorder called Cerebral Aneurysm (or also Brain Aneurysm) which is a medical condition consisting in an abnormal bulging outward of one of the arteries in the brain. The initial attention is given to the human cardiovascular system, a description of which is fatal for understanding the problem of brain aneurysm. The next attention is focused on the solution of eliminating the tension within the aneurysm by using knowledge gained in lectures "Flexibility and Strength II" during the sixth semester. The last chapter shows a summary of three works dealing with computational modeling of cerebral aneurysm.
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Computational modelling of stresses in intracranial aneurysms
Turčanová, Michaela ; Polzer, Stanislav (referee) ; Burša, Jiří (advisor)
The diploma thesis deals with the assessment of the prediction of brain aneurysm rupture based on its geometrical and material properties. In the first part of the thesis there is a~detailed research study of cardiovascular systems with a focus on the cerebral artery and aneurysm occurring on their bifurcates. The second part of the thesis is focused on the creation of two models of arterial cerebral bifurcation with the presence of aneurysm and on obtaining their geometry in unloaded state. Emphasis is placed on the most realistic constitutive model of the artery wall material based on real data from uniaxial tensile tests and on a suitably chosen blood pressure load. This blood pressure may be step-changed, for example, in bungee jumping. In the work, a calculation of the increase in blood pressure during the step-change is performed, which is subsequently used in calculations of tension in the wall of the cerebral aneurysm. In conclusion, the risk of rupture is evaluated in two model idealized brain aneurysms and a discussion of the credibility of the results is given.
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Influence of the surrounding tissue on the stresses in brain arterial aneurysms
Lipenský, Zdeněk ; Burša, Jiří (referee) ; Polzer, Stanislav (advisor)
This thesis is focused on stress in brain aneurysms. It consists of three parts. First part is aimed for gaining information about the topic from scientific resources. Next part consists of analyses of geometry of cerebral aneurysms on the computed wall stress. Analyses are performed on four basic geometrical models and results are being discussed. The risky areas in each investigated shape have been identified as well as the comparisons of stress between those shapes have been performed and the most dangerous shape among investigated shapes has been determined. Third part investigates the influence of surrounding tissue on the brain aneurysm. Conclusion of this thesis is that brain gray tissue has positive yet negligible effect on the computed wall stress.
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Computational modelling of stresses in intracranial aneurysms
Turčanová, Michaela ; Polzer, Stanislav (referee) ; Burša, Jiří (advisor)
The diploma thesis deals with the assessment of the prediction of brain aneurysm rupture based on its geometrical and material properties. In the first part of the thesis there is a~detailed research study of cardiovascular systems with a focus on the cerebral artery and aneurysm occurring on their bifurcates. The second part of the thesis is focused on the creation of two models of arterial cerebral bifurcation with the presence of aneurysm and on obtaining their geometry in unloaded state. Emphasis is placed on the most realistic constitutive model of the artery wall material based on real data from uniaxial tensile tests and on a suitably chosen blood pressure load. This blood pressure may be step-changed, for example, in bungee jumping. In the work, a calculation of the increase in blood pressure during the step-change is performed, which is subsequently used in calculations of tension in the wall of the cerebral aneurysm. In conclusion, the risk of rupture is evaluated in two model idealized brain aneurysms and a discussion of the credibility of the results is given.
|
|
|
Influence of the surrounding tissue on the stresses in brain arterial aneurysms
Lipenský, Zdeněk ; Burša, Jiří (referee) ; Polzer, Stanislav (advisor)
This thesis is focused on stress in brain aneurysms. It consists of three parts. First part is aimed for gaining information about the topic from scientific resources. Next part consists of analyses of geometry of cerebral aneurysms on the computed wall stress. Analyses are performed on four basic geometrical models and results are being discussed. The risky areas in each investigated shape have been identified as well as the comparisons of stress between those shapes have been performed and the most dangerous shape among investigated shapes has been determined. Third part investigates the influence of surrounding tissue on the brain aneurysm. Conclusion of this thesis is that brain gray tissue has positive yet negligible effect on the computed wall stress.
|
|
|
Literature search of possibilities of computational modelling of brain aneurysms
Lipenský, Zdeněk ; Polzer, Stanislav (referee) ; Burša, Jiří (advisor)
This bachelor thesis is focused on gathering general information about a cerebrovascular disorder called Cerebral Aneurysm (or also Brain Aneurysm) which is a medical condition consisting in an abnormal bulging outward of one of the arteries in the brain. The initial attention is given to the human cardiovascular system, a description of which is fatal for understanding the problem of brain aneurysm. The next attention is focused on the solution of eliminating the tension within the aneurysm by using knowledge gained in lectures "Flexibility and Strength II" during the sixth semester. The last chapter shows a summary of three works dealing with computational modeling of cerebral aneurysm.
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