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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Reconstruction of DNA Sequences Containing Repetitive Patterns
 Dvořáček, Vojtěch ; Vogel, Ivan (referee) ; Martínek, Tomáš (advisor)
This bachelor thesis focuses on reconstruction of repetitive patterns in DNA sequences. Although it is motivated by need to create automated tool for telomere characterization in plant  genomes, its goal is creating general solution of given problem. Suggested solution is based on k-mer analysis, which is alignment free method. Its greatest advantage lies in possibility to reconstruct repetitive patterns from NGS sequencing data. Within the scope of this work was designed and iplemented solution, which is able to automatically estiamte suitable parametres for k-mer analysis from input data and optimize them by local state space search method.
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Reconstruction of DNA Sequences Containing Repetitive Patterns
 Dvořáček, Vojtěch ; Vogel, Ivan (referee) ; Martínek, Tomáš (advisor)
This bachelor thesis focuses on reconstruction of repetitive patterns in DNA sequences. Although it is motivated by need to create automated tool for telomere characterization in plant  genomes, its goal is creating general solution of given problem. Suggested solution is based on k-mer analysis, which is alignment free method. Its greatest advantage lies in possibility to reconstruct repetitive patterns from NGS sequencing data. Within the scope of this work was designed and iplemented solution, which is able to automatically estiamte suitable parametres for k-mer analysis from input data and optimize them by local state space search method.
Detailed record

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