|
|
Toxicity study of antimicrobial wound dressings and perspective novel nanomaterials
Kozlíčková, Hana ; Vojtová, Lucy (referee) ; Zajíčková, Lenka (advisor)
This bachelor thesis deals with the study of toxicity of selected commercial antimicrobial wound dressings (StopBac STERILE, containing silver ions and Traumacel Biodress Disinfect, containing chlorhexidine) and antimicrobial nanomaterial, provided by CEITEC BUT laboratories. The experimental part of the work describes the preparation of this polycaprolactone nanomaterial, on which a layer of copper was subsequently deposited by the magnetron sputtering system BESTEC (MAGNETRON). Furthermore, a method was designed to study the cytotoxicity of individual shelters with antimicrobial additives. These tests were performed in vitro on cell cultures by leaching the materials in the laboratories of the Faculty of Science, Masaryk University in Brno. We found that, with the exception of chlorhexidine, low concentrations of active substances extracted from the materials promoted the proliferation of the studied cells, while at high concentrations there were also cytotoxic effects. The analysis of individual materials was also performed using scanning electron microscopy and energy dispersive X-ray spectroscopy.
|
|
|
Toxicity study of antimicrobial wound dressings and perspective novel nanomaterials
Kozlíčková, Hana ; Vojtová, Lucy (referee) ; Zajíčková, Lenka (advisor)
This bachelor thesis deals with the study of toxicity of selected commercial antimicrobial wound dressings (StopBac STERILE, containing silver ions and Traumacel Biodress Disinfect, containing chlorhexidine) and antimicrobial nanomaterial, provided by CEITEC BUT laboratories. The experimental part of the work describes the preparation of this polycaprolactone nanomaterial, on which a layer of copper was subsequently deposited by the magnetron sputtering system BESTEC (MAGNETRON). Furthermore, a method was designed to study the cytotoxicity of individual shelters with antimicrobial additives. These tests were performed in vitro on cell cultures by leaching the materials in the laboratories of the Faculty of Science, Masaryk University in Brno. We found that, with the exception of chlorhexidine, low concentrations of active substances extracted from the materials promoted the proliferation of the studied cells, while at high concentrations there were also cytotoxic effects. The analysis of individual materials was also performed using scanning electron microscopy and energy dispersive X-ray spectroscopy.
|
|
|
Archaeological evidence of medieval armour in the Czech Republik
NOVÁK, Karel
Diese Arbeit beschäftigt sich mit dem Thema mittelalterliche Rüstungen aus archäologischem Blick. Eines der wichtigsten Ziele dieser Arbeit ist es, die archäologischen Funde zu sammeln, sie dann weiter zu verarbeiten und in einzelne Rüstungsgruppen zu klassifizieren, wie zum Beispiel Kettenrüstung, Lamellen- und Plattenpanzer. Zu diesen gehören auch zwei alleinstehende Gruppen: Schilde und Helmen. Es gibt auch das Bemühen, aus diesen Angaben den gegenwärtigen Forschungszustand auszuwerten.
|
|
|
The care of skin in Anaestheziology - resuscitation department and Intensive care unit
MUŽÍKOVÁ, Eva
My Bachelor Paper, focused as indicated in the title, relied on questionnaires distributed among nurses to find out whether they could access with sufficient readiness the anti-decubitus aids and hygiene agents needed for proper care of the patients. Moreover, through inconspicuous observation I tried to make sure the patients had the aids readily available. The first hypothesis, proved warranted, predicted that the nurses took proper care of the patients' skin in conformity to the relevant nursing standards. This hypothesis could be confirmed because I had a chance of reading standards used to regulate practices at the health-care facility being investigated. The nurses had available an adequate range of aids required to adjust the patients' positions, keep the patients clean and take care of their skin. The second hypothesis predicted that the ARW and ICU patients had available the anti-decubitus aids. Now, with the questionnaires reviewed and the observation completed, I can conclude that this hypothesis has been confirmed as well. I believe, the care is also dependent on sufficient supply of bedclothes available the wards and units; judging from my observation and the questionnaires returned by some selected nurses, the bedclothes are in no short supply. The occurrence of decubitus ulcers in these patients is not extremely widespread, and their injuries heal mostly per primam. The nurses try to improve their relevant qualifications by reading vocational periodicals and attending thus oriented seminars - obviously, they pay proper attention to these issues. The Paper endeavored to map the care of skin provided by nurses at the AR Ward and the IC Unit. In my opinion this objective has been met. To get a better idea of my research results, please see the related charts.
|
|
| |
guest ::
