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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Monoklonální bílkoviny u mnohočetného myelomu
 LIDUCHOVÁ, Tereza
Multiple myeloma is a malignant cancer of plasma cells producing monoclonal immunoglobulins - paraproteins. It affects mainly older population. The basic method of determining this disease include protein electrophoresis and determination of free light chains. The practical part of my work is focused on monitoring response to chemotherapy in multiple myeloma paraprotein by the determination and the determination of free light chains and, also whether these two parameters give the same information or not.
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Are silkworm males capable of producing vitellogenin?
 VRCHOTOVÁ, Markéta
The eggs of the silkworm, Bombyx mori, obtained from the ovaries implanted into male hosts are able to complete embryonic and post-embryonic development in spite of the very low amount of vitellogenin. Using polyacrylamide gel electrophoresis, I searched for differences between the protein spectra of eggs from standard females and the eggs from ovaries implanted into the males. I also examined the variability of protein spectra in the eggs of several parthenoclones. I confirmed great differences in the egg protein spectra between the eggs from females and those from the ovaries implanted into males. Both heavy (180 kDa) and light (42 kDa) subunits of vitellogenin were present in the eggs from females but only the heavy subunit of vitellogenin was found in the eggs developed in ovaries implanted into male hosts. Interesting interactions between transplanted gonads and the host milieu were observed. All compared parthenoclones contained similar patterns of the main yolk proteins but differed slightly in some high-molecular weight protein fractions.
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